LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "synthesis trisubstituted" as a keyword



SiO2@Benzothiazole‐Cl@Fc as an Efficient Heterogeneous Catalyst for the Synthesis of 1,3,5‐Trisubstituted Pyrazoles by A3 Coupling

Sign Up to like & get
recommendations! Published in 2025 at "ChemistryOpen"

DOI: 10.1002/open.202500024

Abstract: This research introduces the preparation and analysis of a newly heterogeneous catalyst developed silica nanospheres supporting a ferrocene‐containing ionic liquid (IL) (SiO2@Benzothiazole‐Cl@Fc) for the A3 coupling reaction. The catalyst facilitates the efficient synthesis of 1,3,5‐trisubstituted… read more here.

Keywords: catalyst; sio2 benzothiazole; trisubstituted pyrazoles; synthesis trisubstituted ... See more keywords

REGIOSELECTIVE SYNTHESIS OF 1,3,5-TRISUBSTITUTED PYRAZOLES CONTAINING AN ANTHRANILIC ACID MOTIF

Sign Up to like & get
recommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"

DOI: 10.1007/5109

Abstract: An effective method was developed for the synthesis of 1,3,5-trisubstituted pyrazoles by using acetylenic ketones, obtained from ethyl 5-ethynylanthranilate, in reactions with substituted hydrazines and hydrazides. It was shown that the cyclization of ethyl 5-(3-aryl-3-oxopropinyl)anthranilates… read more here.

Keywords: containing anthranilic; pyrazoles containing; trisubstituted pyrazoles; synthesis trisubstituted ... See more keywords
Photo from archive.org

A facile synthesis of trisubstituted allenamides by DBU-promoted isomerization of propargylamides

Sign Up to like & get
recommendations! Published in 2020 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2020.152146

Abstract: Abstract Trisubstituted allenamides are synthesized by the isomerization of propargylamides with DBU. The reactions afforded a variety of substituted allenamides under simple and mild conditions. One-pot synthesis of allenamides from propargylamines, which were easily prepared… read more here.

Keywords: facile synthesis; isomerization propargylamides; trisubstituted allenamides; synthesis trisubstituted ... See more keywords

Synthesis of Trisubstituted Furans via Copper(I)-Catalyzed Strain-Driving Cycloisomerization/Annulative Fragmentation.

Sign Up to like & get
recommendations! Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c00578

Abstract: The in situ formed furan-fused cyclobutenes via Cu(I)-catalyzed cycloisomerization of readily available allenyl ketones bearing a cyclopropyl moiety are a highly reactive and powerful species, which undergo annulative fragmentation with terminal ynones to afford a… read more here.

Keywords: synthesis trisubstituted; trisubstituted furans; strain; cycloisomerization ... See more keywords

Synthesis of Trisubstituted Oxazoles via Aryne Induced [2,3] Sigmatropic Rearrangement-Annulation Cascade.

Sign Up to like & get
recommendations! Published in 2022 at "Organic letters"

DOI: 10.1021/acs.orglett.2c01379

Abstract: A transition-metal-free, [2,3] sigmatropic rearrangement-annulation cascade of 2-substituted thio/amino acetonitriles with arynes allowing the synthesis of 2,4,5-trisubstituted oxazoles under mild conditions has been demonstrated. The key sulfur/nitrogen ylides were generated by the initial S/N arylation… read more here.

Keywords: synthesis trisubstituted; rearrangement annulation; annulation cascade; rearrangement ... See more keywords

Stereospecific Synthesis of 1,2,3-Trisubstituted Cyclopropanes from Pseudoglycals.

Sign Up to like & get
recommendations! Published in 2025 at "Organic letters"

DOI: 10.1021/acs.orglett.5c00580

Abstract: Strategic design for constructing optically pure 1,2,3-trisubstituted cyclopropanes with three contiguous stereocenters represents a formidable challenge in synthetic organic chemistry. Herein, we report a simple and highly enantiospecific transformation of pseudoglycals into chiral 1,2,3-trisubstituted cyclopropanes,… read more here.

Keywords: chemistry; stereospecific synthesis; synthesis trisubstituted; cyclopropanes pseudoglycals ... See more keywords

EtOC(S)SK-Promoted Retrograde Aldol Condensation for the Synthesis of Trisubstituted Benzenes.

Sign Up to like & get
recommendations! Published in 2025 at "Organic letters"

DOI: 10.1021/acs.orglett.5c02066

Abstract: We herein report a novel multicomponent retrograde aldol condensation reaction for the synthesis of trisubstituted benzenes. Density functional theory calculations indicated a novel reaction mechanism with distinct selectivity that proceeds through three sequential stages: initial… read more here.

Keywords: retrograde aldol; synthesis trisubstituted; trisubstituted benzenes; aldol condensation ... See more keywords
Photo by bermixstudio from unsplash

Catalytic One-Pot Synthesis of Trisubstituted Allenes from Terminal Alkynes and Ketones.

Sign Up to like & get
recommendations! Published in 2017 at "Organic letters"

DOI: 10.1021/acs.orglett.7b02443

Abstract: An efficient one-pot synthesis of trisubstituted allenes from readily available terminal alkynes and ketones is realized. A wide range of trisubstituted allenes may be synthesized efficiently via this method. Preliminary mechanistic studies revealed that CuI… read more here.

Keywords: alkynes ketones; one pot; pot synthesis; terminal alkynes ... See more keywords
Photo by bermixstudio from unsplash

Enantioselective Synthesis of 2,2,3-Trisubstituted Indolines via Bimetallic Relay Catalysis of α-Diazoketones with Enones.

Sign Up to like & get
recommendations! Published in 2018 at "Organic letters"

DOI: 10.1021/acs.orglett.8b01744

Abstract: An efficient asymmetric intramolecular trapping of ammonium ylides of α-diazoketones with enones to synthesize indoline derivatives was realized. A Rh(II)/chiral N,N'-dioxide-Sc(III) complex bimetallic relay catalytic system was established. A series of optically active 2,2,3-trisubstituted indolines… read more here.

Keywords: trisubstituted indolines; synthesis trisubstituted; bimetallic relay; diazoketones enones ... See more keywords
Photo by bermixstudio from unsplash

Synthesis of Trisubstituted Alkenyl Boronic Esters from Alkenes Using the Boryl-Heck Reaction.

Sign Up to like & get
recommendations! Published in 2018 at "Organic letters"

DOI: 10.1021/acs.orglett.8b02949

Abstract: The direct borylation of disubstituted alkenes is reported. These conditions allow for the conversion of a variety 1,1- and 1,2-disubstituted alkenes to trisubstituted alkenyl boronic esters with outstanding yields and excellent E/ Z selectivities. The… read more here.

Keywords: synthesis trisubstituted; boryl heck; reaction; boronic esters ... See more keywords

Cu(I)-Catalyzed stereoselective synthesis of trisubstituted Z-enol esters via interrupting the 1,3-O-transposition reaction

Sign Up to like & get
recommendations! Published in 2018 at "Organic chemistry frontiers"

DOI: 10.1039/c8qo00664d

Abstract: An efficient Cu(I)-catalyzed stereoselective synthesis of trisubstituted Z-enol esters via interrupting the 1,3-O-transposition process is reported. This method provided a convenient approach to highly functionalized Z-enol esters with mild reaction conditions and wide substrate scope. read more here.

Keywords: trisubstituted enol; esters via; stereoselective synthesis; catalyzed stereoselective ... See more keywords