Synthesis of 6-unsubstituted 2-oxo, 2-thioxo, and 2-amino-3,4-dihydropyrimidines and their antiproliferative effect on HL-60 cells
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DOI: 10.1016/j.tetlet.2020.151967
Abstract: Abstract A general and efficient synthetic method for 6-unsubstituted 3,4-dihydropyrimidin-2(1H)-thiones 6 and -ones 7 has been developed. In three-component reactions, the reactivity of reagents serving as the C5–C6 fragment of the dihydropyrimidine ring was compared.… read more here.
Keywords: unsubstituted oxo; antiproliferative effect; thioxo amino; effect ... See more keywords
Synthesis of N-Unsubstituted and N3-Substituted Quinazoline-2,4(1H,3H)-diones from o-Aminobenzamides and CO2 at Atmospheric Pressure and Room Temperature.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00614
Abstract: The unprecedented metal-free synthesis of both N-unsubstituted and N3-substituted quinazoline-2,4(1H,3H)-diones from o-aminobenzamides and CO2 under atmospheric pressure at room temperature is developed. This protocol easily allows for variations of functional groups (including alkyl, aryl, and… read more here.
Keywords: substituted quinazoline; unsubstituted substituted; synthesis unsubstituted; diones aminobenzamides ... See more keywords
Synthesis of N-unsubstituted cycloalkylimines containing a 4 to 8-membered ring.
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DOI: 10.1039/c9cc01755k
Abstract: Primary cycloalkylimines with a 4 to 8-membered ring were synthesized by dehydrocyanation of the corresponding α-aminonitriles on solid potassium hydroxide via a vacuum gas-solid reaction. Imine-enamine tautomerism has been demonstrated at room temperature for the… read more here.
Keywords: containing membered; membered ring; cycloalkylimines containing; unsubstituted cycloalkylimines ... See more keywords
Green synthesis of C5–C6-unsubstituted 1,4-DHP scaffolds using an efficient Ni–chitosan nanocatalyst under ultrasonic conditions
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.18.14
Abstract: A heterogeneous and magnetically recyclable Ni–chitosan nanocatalyst was synthesized and thoroughly characterized by powder Fourier-transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), high-resolution transmission electron microscopy (HRTEM), energy-dispersive X-ray (EDX) spectroscopy,… read more here.
Keywords: synthesis unsubstituted; spectroscopy; microscopy; green synthesis ... See more keywords