Synthesis of new alkoxysilyl-substituted carboranes
Sign Up to like & getrecommendations! Published in 2017 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-017-1826-4
Abstract: New 1,7-bis(trialkoxysilylpropyl)-m-carboranedicarboxamides were synthesized by the reaction of 3-aminopropyltrialkoxysilanes with either m-carboranedicarboxylic acid chloride in the presence of Et3N or m-carboranedicarboxylic acid in the presence of N,N´-carbonyl-diimidazole. The synthesized compounds are colorless liquids soluble in… read more here.
Keywords: alkoxysilyl substituted; synthesis new; new alkoxysilyl; synthesized compounds ... See more keywords
Fluorene Derivatives with Multi-addressable Properties: Synthesis, Characterization, and Reactivity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Surfactants and Detergents"
DOI: 10.1007/s11743-017-1958-4
Abstract: A series of novel fluorene derivatives were synthesized from the target compound N-octadecyl-9-oxo-9H-fluorene-4-carboxamide (3), which led to new functionalized five- and six-membered heterocyclic derivatives via reaction with various reagents. The synthesized compounds were allowed to… read more here.
Keywords: properties synthesis; derivatives multi; synthesized compounds; fluorene derivatives ... See more keywords
Synthesis, molecular docking and molecular dynamics studies of novel tacrine-carbamate derivatives as potent cholinesterase inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105225
Abstract: In the present study, new tacrine derivatives containing carbamate group were synthesized and their acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition activities were evaluated. All synthesized compounds inhibited both cholinesterases at nanomolar level. Among them, ((1,2,3,4-tetrahydroacridin-9-yl)amino)ethyl(3-nitrophenyl)… read more here.
Keywords: synthesized compounds; buche; carbamate derivatives; carbamate ... See more keywords
Experimental and computational study of naphthalimide derivatives: Synthesis, optical, nonlinear optical and antiviral properties
Sign Up to like & getrecommendations! Published in 2021 at "Optik"
DOI: 10.1016/j.ijleo.2021.167748
Abstract: The nonlinear optical (NLO) and antiviral properties of naphthalimide Schiff base compounds (5a–c) were experimentally and computationally investigated. The synthesized compounds (5a–c) were successfully characterized via UV–Vis, FTIR, 1H-NMR, fluorescence spectroscopy, and elemental analysis. The… read more here.
Keywords: naphthalimide derivatives; synthesized compounds; computational study; experimental computational ... See more keywords
Pyridine coupled pyrazole analogues as lethal weapon against MRSA: An in-vitro and in-silico approach.
Sign Up to like & getrecommendations! Published in 2022 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2022.105508
Abstract: The treatment of Methicillin-resistant staphylococcus aureus (MRSA) infections has become challenging due to the growth of multidrug resistance in the bacteria. Here we report the synthesis of pyridine-coupled pyrazoles as an antimicrobial agent against MRSA.… read more here.
Keywords: study; pyrazole analogues; pyridine; coupled pyrazole ... See more keywords
Sulfonamide hybrid schiff bases of anthranilic acid: Synthesis, characterization and their biological potential
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.02.056
Abstract: Abstract In the present work, the novel Schiff bases (03–20) of 4-chloro-N-[2-(hydrazinocarbonyl) phenyl]benzenesulfonamide (02) were synthesized by reacting it with various aldehydes. 4-Chloro-N-[2-(hydrazinocarbonyl) phenyl]benzenesulfonamide (02) was synthesized by reacting methyl 2-{[(4-chlorophenyl)sulfonyl]amino}benzoate (01) with hydrazine. All… read more here.
Keywords: synthesized compounds; sulfonamide hybrid; inhibition; schiff bases ... See more keywords
Design and synthesis of novel pyrazolone based coordination compounds: DNA synergy, biological screening, apoptosis, molecular docking and in-silico ADMET profile
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.07.059
Abstract: Abstract In this research, eight biologically significant novel mixed ligand complexes were prepared from 9-Anthraldehyde, 4-Aminoantipyrine, 1,10-Phenanthroline and metal chlorides. The synthesized compounds were characterized by different physicochemical and multispectral investigation and revealed that the… read more here.
Keywords: synthesized compounds; molecular docking; dna synergy; screening ... See more keywords
Synthesis, characterization, pharmacological evaluation and molecular docking studies of benzothiazole azo derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128477
Abstract: Abstract A series of novel benzothiazole based azo dyes were synthesized and fully characterized by using different analytical techniques. The antioxidant activity of synthesized azo dyes was studied with the DPPH, hydrogen peroxide, metal chelating… read more here.
Keywords: characterization pharmacological; synthesized compounds; synthesized azo; pharmacological evaluation ... See more keywords
Novel 2,6-disubstituted pyridine hydrazones: Synthesis, anticancer activity, docking studies and effects on caspase-3-mediated apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128962
Abstract: Abstract Novel pyridine-based dihydrazones (3a-l) were synthesized by the condensation of appropriate aldehydes and pyridine-2,6-dicarbohydrazide (2) which was obtained by the treatment of dimethyl pyridine-2,6-dicarboxylate (1) with hydrazine hydrate. Structures of all the synthesized compounds… read more here.
Keywords: novel; cell line; synthesized compounds; compound ... See more keywords
Rational synthesis and characterization of medicinal phenyl diazenyl-3-hydroxy-1h-inden-1-one azo derivatives and their metal complexes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.129574
Abstract: Abstract The emergence of resistance to the major classes of antibacterial drug is recognized as serious health concern. So the development of new and more effective antimicrobial agents are necessary for human health. In this… read more here.
Keywords: synthesized compounds; metal complexes; synthesis; azo derivatives ... See more keywords
Design, Synthesis, and Structural Characterization of Thioflavones and Thioflavonols as Potential Tyrosinase Inhibitors: In Vitro and In Silico Studies
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01841
Abstract: To find new potential tyrosinase inhibitors, a diverse range of 2-arylchromone-4-thione derivatives (2a–2p) were designed and synthesized by employing a multistep strategy, and the newly synthesized compounds, for the first time, were screened in vitro… read more here.
Keywords: thioflavones thioflavonols; design synthesis; potential tyrosinase; tyrosinase inhibitors ... See more keywords