Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.08.013
Abstract: Aminoacyl-tRNA synthetases (AARSs) ligate amino acids to their cognate tRNAs during protein synthesis. In humans, eight AARSs and three non-enzymatic AARS-interacting multifunctional proteins (AIMP1-3), which are involved in various biological processes, form a multi-tRNA synthetase… read more here.
Keywords: drs; gst; trna synthetase; synthetase complex ... See more keywords
Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
Sign Up to like & getrecommendations! Published in 2022 at "Translational Oncology"
DOI: 10.1016/j.tranon.2022.101392
Abstract: Highlights • Aminoacyl-tRNA synthetases (AARSs) of multi-tRNA synthetase complex (MSC) are involved in cancer pathogenesis.• The scaffolding proteins of MSC have mainly anti-tumorigenic functions whereas the MSC associated AARSs have pro-tumorigenic roles.• MSC release of… read more here.
Keywords: multi trna; aminoacyl trna; trna synthetases; trna synthetase ... See more keywords