Mass cytometry reveals an impairment of B cell homeostasis in anti-synthetase syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.04.014
Abstract: Recent data suggest the implication of T, B and NK cells in the anti-synthetase syndrome (ASyS); nevertheless their role and activation states are poorly described. We performed deep immune-profiling using 37 markers on peripheral blood… read more here.
Keywords: mass cytometry; asys patients; anti synthetase; cytometry reveals ... See more keywords
Clinical experience in anti-synthetase syndrome: a monocentric retrospective analytical study.
Sign Up to like & getrecommendations! Published in 2021 at "Acta clinica Belgica"
DOI: 10.1080/17843286.2021.1925818
Abstract: OBJECTIVES: Anti-synthetase syndrome (ASS) is a rare autoimmune disorder combining autoantibodies and specific clinical manifestations. One of the particularities of ASS is the pleiomorphic radiological presentation seen at the initial work-up. Evaluating treatment response can… read more here.
Keywords: anti synthetase; study; clinical experience; synthetase syndrome ... See more keywords
Predictive factors for progressive fibrosing interstitial lung disease in anti‐synthetase syndrome
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14664
Abstract: Interstitial lung disease (ILD) is common in anti‐synthetase syndrome (ASS). Progressive fibrosing ILD (PF‐ILD) may develop in ILD with autoimmune features. Data on PF‐ILDs in ASS as a group are scarce. This study aimed to… read more here.
Keywords: progressive fibrosing; lung disease; synthetase syndrome; interstitial lung ... See more keywords
Anti-synthetase syndrome-associated pulmonary veno-occlusive disease
Sign Up to like & getrecommendations! Published in 2020 at "Pulmonary Circulation"
DOI: 10.1177/2045894020935289
Abstract: Pulmonary arterial hypertension has been reported with a prevalence of 7.9% in patients with anti-synthetase syndrome; however, anti-synthetase syndrome associated with pulmonary veno-occlusive disease (PVOD) has never before been described in the literature. We present… read more here.
Keywords: syndrome associated; synthetase syndrome; anti synthetase; hypertension ... See more keywords
Single-Cell Transcriptomics Reveals Peripheral Immune Responses in Anti-Synthetase Syndrome-Associated Interstitial Lung Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.804034
Abstract: Objective Interstitial lung diseases (ILDs) secondary to anti-synthetase syndrome (ASS) greatly influence the prognoses of patients with ASS. Here we aimed to investigate the peripheral immune responses to understand the pathogenesis of this condition. Methods… read more here.
Keywords: ass ild; interstitial lung; anti synthetase; patients ass ... See more keywords
Aminoacyl-tRNA Synthetases: On Anti-Synthetase Syndrome and Beyond
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.866087
Abstract: Anti-synthetase syndrome (ASSD) is an autoimmune disease characterized by the presence of autoantibodies targeting one of several aminoacyl t-RNA synthetases (aaRSs) along with clinical features including interstitial lung disease, myositis, Raynaud’s phenomenon, arthritis, mechanic’s hands,… read more here.
Keywords: assd; trna synthetases; synthetase syndrome; aminoacyl trna ... See more keywords
Comparison of cytokine/chemokine profiles between dermatomyositis and anti-synthetase syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.1042580
Abstract: Objectives Dermatomyositis (DM) and anti-synthetase syndrome (ASS) are autoimmune diseases with multisystem involvement. Despite sharing some clinical and myopathological features, these are two diseases with different pathogeneses and prognoses. We aimed to clarify and compare… read more here.
Keywords: chemokine; dermatomyositis anti; cytokine chemokine; synthetase syndrome ... See more keywords