Synthetic Antibiotic Derived from Sequences Encrypted in a Protein from Human Plasma.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c04496
Abstract: Encrypted peptides have been recently found in the human proteome and represent a potential class of antibiotics. Here we report three peptides derived from the human apolipoprotein B (residues 887-922) that exhibited potent antimicrobial activity… read more here.
Keywords: derived sequences; synthetic antibiotic; antibiotic derived; sequences encrypted ... See more keywords
The Novel Synthetic Antibiotic BDTL049 Based on a Dendritic System Induces Lipid Domain Formation while Escaping the Cell Envelope Stress Resistance Determinants
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15010297
Abstract: The threat of antimicrobial-resistant bacteria is ever increasing and over the past-decades development of novel therapeutic counter measurements have virtually come to a halt. This circumstance calls for interdisciplinary approaches to design, evaluate and validate… read more here.
Keywords: resistance determinants; novel synthetic; antibiotic bdtl049; synthetic antibiotic ... See more keywords