Synthetic antimicrobial peptides: From choice of the best sequences to action mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.05.016
Abstract: The emergence of antibiotic-resistant microbes has stimulated research worldwide seeking new biologically active molecules. In this respect, synthetic antimicrobial peptides (SAMPs) have been suggested to overcome this problem. Although there are some online servers that… read more here.
Keywords: choice best; best sequences; peptides choice; synthetic antimicrobial ... See more keywords
Delineating the Mechanism of Action of a Protease Resistant and Salt Tolerant Synthetic Antimicrobial Peptide against Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01089
Abstract: Rapidly growing antimicrobial resistance (AMR) against antibiotics has propelled the development of synthetic antimicrobial peptides (AMPs) as potential antimicrobial agents. An antimicrobial peptide Nle-Dab-Trp-Nle-Dab-Dab-Nle-CONH2 (P36; Nle = norleucine, Dab = diaminobutyric acid, Trp = tryptophan)… read more here.
Keywords: protease; pseudomonas aeruginosa; antimicrobial peptide; salt tolerant ... See more keywords
CAMPR4: a database of natural and synthetic antimicrobial peptides
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac933
Abstract: Abstract There has been an exponential increase in the design of synthetic antimicrobial peptides (AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues with physicochemical properties known to be critical… read more here.
Keywords: synthetic amps; database natural; antimicrobial peptides; campr4 database ... See more keywords
Synthetic Antimicrobial Immunomodulatory Peptides: Ongoing Studies and Clinical Trials
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DOI: 10.3390/antibiotics11081062
Abstract: The increasingly widespread antimicrobial resistance forces the search for new antimicrobial substances capable of fighting infection. Antimicrobial peptides (AMPs) and their synthetic analogs form an extensive group of compounds of great structural diversity and multifunctionality,… read more here.
Keywords: idr peptides; antimicrobial immunomodulatory; peptides ongoing; immunomodulatory peptides ... See more keywords
Multitalented Synthetic Antimicrobial Peptides and Their Antibacterial, Antifungal and Antiviral Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010545
Abstract: Despite the great strides in healthcare during the last century, some challenges still remained unanswered. The development of multi-drug resistant bacteria, the alarming growth of fungal infections, the emerging/re-emerging of viral diseases are yet a… read more here.
Keywords: antifungal antiviral; antibacterial antifungal; peptides antibacterial; antimicrobial peptides ... See more keywords