Synthetic Biology Toolkits for Metabolic Engineering of Cyanobacteria
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Journal"
DOI: 10.1002/biot.201800496
Abstract: Cyanobacteria are of great importance to Earth's ecology. Due to their capability in photosynthesis and C1 metabolism, they are ideal microbial chassis that can be engineered for direct conversion of carbon dioxide and solar energy… read more here.
Keywords: metabolic engineering; synthetic biology; biology toolkits; biology ... See more keywords
An in vitro synthetic biology platform for the industrial biomanufacturing of myo‐inositol from starch
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26314
Abstract: Myo‐Inositol (vitamin B8) is widely used in the drug, cosmetic, and food & feed industries. Here, we present an in vitro non‐fermentative enzymatic pathway that converts starch to inositol in one vessel. This in vitro… read more here.
Keywords: myo inositol; inositol; synthetic biology; biology platform ... See more keywords
A synthetic biology approach for the fabrication of functional (fluorescent magnetic) bioorganic–inorganic hybrid materials in sponge primmorphs
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27310
Abstract: During evolution, sponges (Porifera) have honed the genetic toolbox and biosynthetic mechanisms for the fabrication of siliceous skeletal components (spicules). Spicules carry a protein scaffold embedded within biogenic silica (biosilica) and feature an amazing range… read more here.
Keywords: hybrid materials; biology approach; synthetic biology; biology ... See more keywords
“Toehold Switches; a foothold for Synthetic Biology”
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28309
Abstract: Toehold switches are de novo designed riboregulators that contain two RNA components interacting through linear‐linear RNA interactions, regulating the gene expression. These are highly versatile, exhibit excellent orthogonality, wide dynamic range, and are highly programmable,… read more here.
Keywords: switches foothold; foothold synthetic; toehold switches; biology ... See more keywords
CELL FACTORY ENGINEERING: CHALLENGES AND OPPORTUNITIES FOR SYNTHETIC BIOLOGY APPLICATIONS.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28365
Abstract: The production of high-quality recombinant proteins is critical to maintaining a continuous supply of biopharmaceuticals, such as therapeutic antibodies. Engineering mammalian cell factories presents a number of limitations typically associated with the proteotoxic stress induced… read more here.
Keywords: cell factory; factory engineering; engineering; biology ... See more keywords
Synthetic biology in biofilms: Tools, challenges, and opportunities
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Progress"
DOI: 10.1002/btpr.3123
Abstract: The field of synthetic biology seeks to program living cells to perform novel functions with applications ranging from environmental biosensing to smart cell‐based therapeutics. Bacteria are an especially attractive chassis organism due to their rapid… read more here.
Keywords: biology biofilms; biofilms tools; synthetic biology; biology ... See more keywords
Advances in Synthetic Biology of Fungi and Contributions to the Discovery of New Molecules
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300008
Abstract: The sequencing of fungal genomes is becoming increasingly accessible, with a wealth of data already available. In parallel, the prediction of the putative biosynthetic pathways responsible for the synthesis of potential new natural products is… read more here.
Keywords: advances synthetic; fungi contributions; biology fungi; contributions discovery ... See more keywords
Recent advances in natural products exploitation in Streptomyces via synthetic biology
Sign Up to like & getrecommendations! Published in 2019 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201800137
Abstract: Natural products of microbial origin have proven to be the wellspring of clinically useful compounds for human therapeutics. Streptomyces species are predominant sources of bioactive compounds, most of which serve as potential drug candidates. While… read more here.
Keywords: natural products; synthetic biology; advances natural; biology ... See more keywords
Protein and peptide engineering for CEST imaging in the age of Synthetic Biology.
Sign Up to like & getrecommendations! Published in 2022 at "NMR in biomedicine"
DOI: 10.1002/nbm.4712
Abstract: At the beginning of the millennium, the first Chemical Exchange Saturation Transfer (CEST) contrast agents were bio-organic molecules. However, later, metal based CEST agents (paraCEST agents) took center stage. This didn't last too long as… read more here.
Keywords: synthetic biology; cest contrast; biology; cest agents ... See more keywords
Xenobiology: State-of-the-Art, Ethics, and Philosophy of New-to-Nature Organisms.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2016_14
Abstract: The basic chemical constitution of all living organisms in the context of carbon-based chemistry consists of a limited number of small molecules and polymers. Until the twenty-first century, biology was mainly an analytical science and… read more here.
Keywords: synthetic biology; chemistry; philosophy; biology ... See more keywords
Synthetic Biology to Engineer Bacteriophage Genomes.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7395-8_21
Abstract: Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered towards a wide range of applications including… read more here.
Keywords: synthetic biology; bacteriophage; biology engineer; biology ... See more keywords