Control of Astrocyte Quiescence and Activation in a Synthetic Brain Hydrogel.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901419
Abstract: Bioengineers have designed numerous instructive brain extracellular matrix (ECM) environments with tailored and tunable protein compositions and biomechanical properties in vitro to study astrocyte reactivity during trauma and inflammation. However, a major limitation of both… read more here.
Keywords: brain hydrogel; synthetic brain; astrocyte quiescence; activation ... See more keywords
Curcumin and Homotaurine Suppress Amyloid-β25-35 Aggregation in Synthetic Brain Membranes.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00057
Abstract: Amyloid-β (Aβ) peptides spontaneously aggregate into β- and cross-β-sheets in model brain membranes. These nanometer sized can fuse into larger micrometer sized clusters and become extracellular and serve as nuclei for further plaque and fibril… read more here.
Keywords: aggregation; brain membranes; synthetic brain; curcumin homotaurine ... See more keywords