Critical Illness Secondary to Synthetic Cannabinoid Ingestion
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.8516
Abstract: Key Points Question What are the clinical manifestations of synthetic cannabinoid intoxication, and are they life threatening? Findings This case series of 30 adult patients describes the acute neurologic and cardiopulmonary complications of synthetic cannabinoid… read more here.
Keywords: critical illness; illness secondary; synthetic cannabinoid; cannabinoid ... See more keywords
The chemistry and pharmacology of synthetic cannabinoid SDB-006 and its regioisomeric fluorinated and methoxylated analogs.
Sign Up to like & getrecommendations! Published in 2018 at "Drug testing and analysis"
DOI: 10.1002/dta.2362
Abstract: Synthetic cannabinoids are the largest and most structurally diverse class of new psychoactive substances, with manufacturers often using isomerism to evade detection and circumvent legal restriction. The regioisomeric methoxy- and fluorine-substituted analogs of SDB-006 (N-benzyl-1-pentyl-1H-indole-3-carboxamide)… read more here.
Keywords: chemistry; synthetic cannabinoid; regioisomeric; pharmacology ... See more keywords
Metabolic profiling of synthetic cannabinoid 5F-ADB by human liver microsome incubations and urine samples using high-resolution mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2566
Abstract: 5F-ADB (methyl 2-{[1-(5-fluoropentyl)-1H-indazole-3-carbonyl] amino}-3,3-dimethylbutanoate) is a frequently abused new synthetic cannabinoid that has been sold since at least the end of 2014 on the drug market and has been classified as an illicit drug in… read more here.
Keywords: high resolution; synthetic cannabinoid; drug; adb ... See more keywords
Profiling of synthesis-related impurities of the synthetic cannabinoid Cumyl-5F-PINACA in seized samples of e-liquids via multivariate analysis of UHPLC/MSn data.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2673
Abstract: Vaping of synthetic cannabinoids via e-cigarette increasingly grows in popularity. In the presented study, we tentatively identified twelve by-products found in a highly pure sample of the synthetic cannabinoid Cumyl-5F-PINACA (1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide), a prevalent new psychoactive… read more here.
Keywords: cumyl pinaca; analysis; synthetic cannabinoid;
Solid-phase extraction-liquid chromatography-tandem mass spectrometry method for the qualitative analysis of 61 synthetic cannabinoid metabolites in urine.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2680
Abstract: This article comprises the development and validation of a protocol for the qualitative analysis of 61 phase I synthetic cannabinoid metabolites in urine originating from 29 synthetic cannabinoids, combining solid-phase extraction with a reversed phase… read more here.
Keywords: phase; analysis; synthetic cannabinoid; cannabinoid metabolites ... See more keywords
Detection and characterization of the new synthetic cannabinoid APP-BINACA in forensic casework.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2698
Abstract: New psychoactive substances (NPS) continue to emerge around the world. APP-BINACA (or APP-BUTINACA), a novel synthetic cannabinoid, was first reported in Europe in January 2019 and later in the United States in March 2019. APP-BINACA… read more here.
Keywords: app binaca; new synthetic; synthetic cannabinoid; binaca ... See more keywords
Large-scale evaluation of ion mobility spectrometry for the rapid detection of synthetic cannabinoid receptor agonists in infused papers in prisons.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2945
Abstract: Synthetic cannabinoid receptor agonists (SCRAs), colloquially known as "spice," are commonly used in prisons and enter establishments via the mail in the form of infused papers. Many prisons use benchtop Ion Mobility Spectroscopy (IMS) instruments… read more here.
Keywords: detection; infused papers; mobility; synthetic cannabinoid ... See more keywords
A transnational perspective on the evolution of the synthetic cannabinoid receptor agonists market: Comparing prison and general populations.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3002
Abstract: The synthetic cannabinoid receptor agonist (SCRA) market is transnational and the availability of individual SCRAs changes regularly in response to national and international legislative controls. This generates a cyclic pattern and near constant evolution of… read more here.
Keywords: scra; cannabinoid receptor; synthetic cannabinoid; market ... See more keywords
Synthetic cannabinoid receptor agonists and their human metabolites in sewage water: Stability assessment and identification of transformation products.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3129
Abstract: Since their first appearance in 2008, synthetic cannabinoid receptor agonists (SCRAs) remain the most popular new psychoactive substances (NPS) in the EU. Following consumption, these drugs and their metabolites are urinary excreted and enter the… read more here.
Keywords: sewage water; synthetic cannabinoid; receptor agonists; cannabinoid receptor ... See more keywords
Cannabinoid receptor activation potential of the next generation, generic ban evading OXIZID synthetic cannabinoid receptor agonists.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3283
Abstract: In recent years, several nations have implemented various measures to control the surge of new synthetic cannabinoid receptor agonists (SCRAs) entering the recreational drug market. In July 2021, China put into effect a new generic… read more here.
Keywords: poxizid; bzo; synthetic cannabinoid; cannabinoid receptor ... See more keywords
Analysis of Synthetic Cannabinoid Metabolites by Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8823-5_14
Abstract: The analysis of synthetic cannabinoid compounds in a urine sample is currently one of the more complex tasks facing toxicologists. The list of prevalent compounds in circulation at any given time is constantly in flux,… read more here.
Keywords: cannabinoid metabolites; metabolites liquid; synthetic cannabinoid; analysis synthetic ... See more keywords