Variation in commercial smoking mixtures containing third-generation synthetic cannabinoids.
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DOI: 10.1002/dta.1975
Abstract: Variation in ingredients (qualitative variation) and in quantity of active compounds (quantitative variation) in herbal smoking mixtures containing synthetic cannabinoids has been shown for older products. This can be dangerous to the user, as accurate… read more here.
Keywords: mixtures containing; variation; synthetic cannabinoids; smoking mixtures ... See more keywords
Application of an activity-based receptor bioassay to investigate the in vitro activity of selected indole- and indazole-3-carboxamide-based synthetic cannabinoids at CB1 and CB2 receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2517
Abstract: Synthetic cannabinoids (SCs) are the most chemically diverse group of new psychoactive substances. This group has been associated with several intoxications, many with fatal outcomes. Although advancements have been achieved in pharmacology, metabolism, and detection… read more here.
Keywords: synthetic cannabinoids; indole indazole; cb1 cb2; investigate vitro ... See more keywords
Ion mobility spectrometry as a fast screening tool for synthetic cannabinoids to uncover drug trafficking in jail via herbal mixtures, paper, food, and cosmetics.
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DOI: 10.1002/dta.2565
Abstract: The greatest challenge for European drug policies is how to effectively respond to the dynamic and constantly changing market for new psychoactive substances (NPS). Even small modifications in the chemical structure of substances often allow… read more here.
Keywords: synthetic cannabinoids; drug; ion mobility; mobility spectrometry ... See more keywords
Identification of AD-18, 5F-MDA-19, and pentyl MDA-19 in seized materials after the class-wide ban of synthetic cannabinoids in China.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3185
Abstract: To curb the manufacturing, trafficking and abuse of synthetic cannabinoids, China implemented a class-wide regulation on synthetic cannabinoids in July 2021. Recently, three different types of synthetic cannabinoid analogs that were not covered by the… read more here.
Keywords: mda; synthetic cannabinoids; pentyl mda; cannabinoids china ... See more keywords
EMCDDA framework and practical guidance for naming synthetic cannabinoids.
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DOI: 10.1002/dta.3403
Abstract: Synthetic cannabinoids (SCs), often sold as 'legal' replacements for cannabis, are the largest group of new psychoactive substances monitored by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Currently, close to 240 structurally… read more here.
Keywords: scs; emcdda framework; framework practical; practical guidance ... See more keywords
From JWH-018 to OXIZIDS: Structural evolution of synthetic cannabinoids in the European Union from 2008 to present day.
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DOI: 10.1002/dta.3422
Abstract: With new synthetic cannabinoids (SCs) appearing on the European drug market every year, early warning systems are key to detect, monitor, and respond to threats posed by them. The European Union Early Warning System (EU… read more here.
Keywords: scs; european union; structural evolution; union ... See more keywords
Hexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review.
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DOI: 10.1002/dta.3519
Abstract: Since the early 2000s, there has been a turmoil on the global illicit cannabinoid market. Parallel to legislative changes in some jurisdictions regarding herbal cannabis, unregulated and cheap synthetic cannabinoids with astonishing structural diversity have… read more here.
Keywords: pharmacology; hemp; semi synthetic; hexahydrocannabinol closely ... See more keywords
Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids.
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DOI: 10.1007/7854_2016_17
Abstract: Originally developed as research tools for use in structure-activity relationship studies, synthetic cannabinoids contributed to significant scientific advances in the cannabinoid field. Unfortunately, a subset of these compounds was diverted for recreational use beginning in… read more here.
Keywords: combination chemistry; structure activity; chemistry; synthetic cannabinoids ... See more keywords
Distribution of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02493-8
Abstract: New psychoactive substances, especially synthetic cannabinoids (SC), are gaining increasing relevance in postmortem forensic toxicology. Particularly, the interpretation of analytical results is challenging, as usually, no toxicokinetic (TK) data concerning distribution in organs and tissues… read more here.
Keywords: administration; synthetic cannabinoids; jwh 210; rcs ... See more keywords
Study on the metabolic process of synthetic cannabinoids 4F-MDMB-BINACA and 4F-MDMB-BICA in human liver microsome and zebrafish model via UHPLC-QE Orbitrap MS
Sign Up to like & getrecommendations! Published in 2022 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-022-04034-2
Abstract: In order to address the increasing abuse of synthetic cannabinoids, on July 1, 2021, China listed the whole category of synthetic cannabinoids in the Supplementary Catalog for the Control of Non-medicinal Narcotic Drugs and Psychotropic… read more here.
Keywords: mdmb bica; cannabinoids mdmb; synthetic cannabinoids; mdmb binaca ... See more keywords
Phase I metabolic profiling of the synthetic cannabinoids THJ-018 and THJ-2201 in human urine in comparison to human liver microsome and cytochrome P450 isoenzyme incubation
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-018-1964-8
Abstract: Despite the increasing relevance of synthetic cannabinoids as one of the most important classes within “New Psychoactive Substances”, there is still a lack of knowledge concerning their metabolism in humans. Due to the extensive metabolism… read more here.
Keywords: synthetic cannabinoids; 018 thj; thj 2201; metabolism ... See more keywords