An LC-MS/MS methodological approach to the analysis of hair for amphetamine-type-stimulant (ATS) drugs, including selected synthetic cathinones and piperazines.
Sign Up to like & getrecommendations! Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.1948
Abstract: Amphetamine-type-stimulants (ATS) are the second most commonly used group of illicit drugs worldwide. However, in the last few years, new psychoactive substances (NPS) with stimulant effects have appeared on the illegal market, which are not… read more here.
Keywords: synthetic cathinones; amphetamine type; analysis; hair ... See more keywords
The role of diode array ultraviolet detection for the identification of synthetic cathinones.
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DOI: 10.1002/dta.2163
Abstract: The utility of diode array ultraviolet (UV) detection for aiding in the identification of synthetic cathinones, including different sub-classes and positional isomers is presented. For 35 synthetic cathinones, unique UV spectra are obtained for seven… read more here.
Keywords: synthetic cathinones; positional isomers; identification synthetic; ultraviolet detection ... See more keywords
Comparison of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography for the separation of synthetic cathinones.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of separation science"
DOI: 10.1002/jssc.201700349
Abstract: A comparison of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography for the separation of synthetic cathinones has been conducted. Nine different mixtures of bath salts were analyzed in… read more here.
Keywords: chromatography; synthetic cathinones; ultra high; high performance ... See more keywords
From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of toxicology"
DOI: 10.1007/s00204-021-02990-9
Abstract: Synthetic cathinones are among the most popular new psychoactive substances, being abused for their stimulant properties, which are similar to those of amphetamine and 3,4-methylenedioxymethamphetamine (MDMA). Considering that the liver is a likely target for… read more here.
Keywords: butylone; synthetic cathinones; butylone dmmc; buphedrone ... See more keywords
An updated review on synthetic cathinones.
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DOI: 10.1007/s00204-021-03083-3
Abstract: Cathinone, the main psychoactive compound found in the plant Catha edulis Forsk. (khat), is a β-keto analogue of amphetamine, sharing not only the phenethylamine structure, but also the amphetamine-like stimulant effects. Synthetic cathinones are derivatives… read more here.
Keywords: synthetic cathinones; updated review; review synthetic; chemistry ... See more keywords
MDPV-induced aggression in humans not established
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-019-02165-3
Abstract: To the Editors: We read with interest the article by De-Giogio et al. [1] investigating the acute and repeated administration of 3,4methylenedioxypyrovalerone (MDPV) on aggressive responding in mice. This is an important issue because MDPV… read more here.
Keywords: synthetic cathinones; ecologically relevant; induced aggression; aggression ... See more keywords
Rapid tentative identification of synthetic cathinones in seized products taking advantage of the full capabilities of triple quadrupole analyzer
Sign Up to like & getrecommendations! Published in 2018 at "Forensic Toxicology"
DOI: 10.1007/s11419-018-0432-y
Abstract: PurposeIn this work, a new approach for synthetic cathinone identification in seized products, consisting of a rapid pseudo-target screening using liquid chromatography coupled to low-resolution tandem mass spectrometry (MS/MS), is proposed based on typical common product… read more here.
Keywords: synthetic cathinones; identification synthetic; tentative identification; rapid tentative ... See more keywords
Synthetic cathinones and their phenethylamine analogues produce distinct psychomotor and reward behavior in crayfish
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2019.112368
Abstract: Synthetic cathinones share potent sympathomimetic properties with amphetamines due to their shared phenethylamine backbone. Despite recent work focused on understanding the behavioral effects of synthetic cathinones, a systematic comparison of neuropharmacology, behavior, and physiological effects… read more here.
Keywords: synthetic cathinones; behavioral effects; produce distinct; psychomotor ... See more keywords
Emerging Drugs of Abuse: Synthetic Cannabinoids, Phenylethylamines (2C Drugs), and Synthetic Cathinones
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pediatric Emergency Medicine"
DOI: 10.1016/j.cpem.2017.07.009
Abstract: Abstract Emerging drugs of abuse include psychostimulants marketed as household products but containing novel psychoactive substances. These products are easily purchased and frequently change composition in response to regulatory pressure. The synthetic cannabinoids, 2C phenylethylamines,… read more here.
Keywords: synthetic cathinones; synthetic cannabinoids; emerging drugs; abuse synthetic ... See more keywords
Role of amino terminal substitutions in the pharmacological, rewarding and psychostimulant profiles of novel synthetic cathinones
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108475
Abstract: The emergence of new synthetic cathinones continues to be a matter of public health concern. In fact, they are quickly replaced by new structurally related alternatives. The main goal of the present study was to… read more here.
Keywords: synthetic cathinones; role amino; amino terminal; novel synthetic ... See more keywords
Comparison of six derivatizing agents for the determination of nine synthetic cathinones using gas chromatography-mass spectrometry
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DOI: 10.1039/c7ay00597k
Abstract: Six acylation reagents have been compared for their derivatisation potential towards nine synthetic cathinones by gas chromatography-mass spectrometry (GC-MS). The evaluated reagents were pentafluoropropionic anhydride (PFPA), trifluoroacetic anhydride (TFA), chlorodifluoroacetic anhydride (CLF2AA), heptafluorobutyric anhydride (HFBA),… read more here.
Keywords: synthetic cathinones; gas chromatography; derivatizing agents; mass spectrometry ... See more keywords