Artificial Cytoskeleton Assembly for Synthetic Cell Motility.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200437
Abstract: Imitation of cellular processes in cell-like compartments is a current research focus in synthetic biology. Here, we introduce a method for assembling an artificial cytoskeleton in a synthetic cell model system based on a poly(N-isopropylacrylamide)… read more here.
Keywords: synthetic cell; artificial cytoskeleton; cytoskeleton; biology ... See more keywords
Toward synthetic life: Biomimetic synthetic cell communication.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.08.008
Abstract: Engineering synthetic minimal cells provide a controllable chassis for studying the biochemical principles of natural life, increasing our understanding of complex biological processes. Recently, synthetic cell engineering has enabled communication between both natural live cells… read more here.
Keywords: engineering; communication; synthetic cell; life ... See more keywords
Targeted bacterial conjugation mediated by synthetic cell-to-cell adhesions
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1164
Abstract: Abstract Genetic interventions on microbiomes, for clinical or biotechnological purposes, remain challenging. Conjugation-based delivery of genetic cargo is still unspecific and limited by low conjugation rates. Here we report an approach to overcome these problems,… read more here.
Keywords: cell; synthetic cell; targeted bacterial; bacterial conjugation ... See more keywords
Parasites, Infections, and Inoculation in Synthetic Minimal Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1101/2022.05.11.491559
Abstract: Synthetic minimal cells provide a controllable and engineerable model for an increasing amount of biological processes. While much simpler than any live natural cell, synthetic cells offer a chassis for investigating the foundations of key… read more here.
Keywords: minimal cells; synthetic cell; host; synthetic minimal ... See more keywords
Scientific iconoclasm and active imagination: synthetic cells as techno-scientific mandalas
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences, Society and Policy"
DOI: 10.1186/s40504-018-0075-0
Abstract: Metaphors allow us to come to terms with abstract and complex information, by comparing it to something which is structured, familiar and concrete. Although modern science is “iconoclastic”, as Gaston Bachelard phrases it (i.e. bent… read more here.
Keywords: cell; scientific iconoclasm; synthetic cell; active imagination ... See more keywords
Controlling Synthetic Cell-Cell Communication
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.809945
Abstract: Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic… read more here.
Keywords: cell; controlling synthetic; communication; synthetic cell ... See more keywords
Synthetic, Cell-Derived, Brain-Derived, and Recombinant β-Amyloid: Modelling Alzheimer’s Disease for Research and Drug Development
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315036
Abstract: Alzheimer’s disease (AD) is the most common cause of dementia in the elderly, characterised by the accumulation of senile plaques and tau tangles, neurodegeneration, and neuroinflammation in the brain. The development of AD is a… read more here.
Keywords: synthetic cell; disease; development; alzheimer disease ... See more keywords