Dendrimersome Synthetic Cells Harbor Cell Division Machinery of Bacteria
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202202364
Abstract: The integration of active cell machinery with synthetic building blocks is the bridge toward developing synthetic cells with biological functions and beyond. Self‐replication is one of the most important tasks of living systems, and various… read more here.
Keywords: cell; cell division; division machinery; machinery ... See more keywords
Synthetic cells in biomedical applications.
Sign Up to like & getrecommendations! Published in 2021 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1761
Abstract: Synthetic cells are engineered vesicles that can mimic one or more salient features of life. These features include directed localization, sense-and-respond behavior, gene expression, metabolism, and high stability. In nanomedicine, many of these features are… read more here.
Keywords: cells biomedical; synthetic cells; biology; biomedical applications ... See more keywords
Bottom-Up Assembly of Synthetic Cells with a DNA Cytoskeleton.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10703
Abstract: Cytoskeletal elements, like actin and myosin, have been reconstituted inside lipid vesicles toward the vision to reconstruct cells from the bottom up. Here, we realize the de novo assembly of entirely artificial DNA-based cytoskeletons with… read more here.
Keywords: assembly synthetic; cells dna; dna; bottom assembly ... See more keywords
Programmable Fusion and Differentiation of Synthetic Minimal Cells.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00519
Abstract: Synthetic cells can mimic the intricate complexities of live cells, while mitigating the level of noise that is present natural systems; however, many crucial processes still need to be demonstrated in synthetic cells to use… read more here.
Keywords: programmable fusion; synthetic cells; fusion differentiation; biology ... See more keywords
Actinosomes: Condensate-Templated Containers for Engineering Synthetic Cells
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00290
Abstract: Engineering synthetic cells has a broad appeal, from understanding living cells to designing novel biomaterials for therapeutics, biosensing, and hybrid interfaces. A key prerequisite to creating synthetic cells is a three-dimensional container capable of orchestrating… read more here.
Keywords: templated containers; condensate templated; engineering synthetic; actinosomes condensate ... See more keywords
Imaging Flow Cytometry for High-Throughput Phenotyping of Synthetic Cells.
Sign Up to like & getrecommendations! Published in 2023 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.3c00074
Abstract: The reconstitution of basic cellular functions in micrometer-sized liposomes has led to a surge of interest in the construction of synthetic cells. Microscopy and flow cytometry are powerful tools for characterizing biological processes in liposomes… read more here.
Keywords: imaging flow; flow cytometry; microscopy; high throughput ... See more keywords
Orthogonal Light-Activated DNA for Patterned Biocomputing within Synthetic Cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c02350
Abstract: Cell-free gene expression is a vital research tool to study biological systems in defined minimal environments and has promising applications in biotechnology. Developing methods to control DNA templates for cell-free expression will be important for… read more here.
Keywords: activated dna; cell free; light; light activated ... See more keywords
Synthetic cells produce a quorum sensing chemical signal perceived by Pseudomonas aeruginosa.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c7cc09678j
Abstract: Recent developments in bottom-up synthetic biology (e.g., lipid vesicle technology integrated with cell-free protein expression systems) allow the generation of semi-synthetic minimal cells (in short, synthetic cells, SCs) endowed with some distinctive capacities of natural… read more here.
Keywords: natural cells; synthetic cells; pseudomonas aeruginosa; chemical signal ... See more keywords
Molecular Communications in the Context of “Synthetic Cells” Research
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on NanoBioscience"
DOI: 10.1109/tnb.2018.2882543
Abstract: The recent progresses in bottom-up synthetic biology allow the construction of cell-like systems (also called “synthetic cells”) based on the encapsulation of chemicals and biological macromolecules inside lipid vesicles. Synthetic cells are far from being… read more here.
Keywords: context synthetic; cells research; molecular communications; communications context ... See more keywords
Chemical Neural Networks Inside Synthetic Cells? A Proposal for Their Realization and Modeling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.927110
Abstract: The exciting sci-tech arena of synthetic biology (SB) provides concepts, tools, and approaches for fundamental revolutions in basic and applied research. SB plays a key role when it is conceived as one of the branches… read more here.
Keywords: networks inside; neural networks; chemical neural; synthetic cells ... See more keywords
Controlling Synthetic Cell-Cell Communication
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.809945
Abstract: Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully realise the potential of synthetic… read more here.
Keywords: cell; controlling synthetic; communication; synthetic cell ... See more keywords