Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2021.1901578
Abstract: ABSTRACT Introduction: Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway plays a key role in diverse gene expressions responsible for protection against oxidative stress and xenobiotics. Chalcones with a common chemical scaffold of 1,3-diaryl-2-… read more here.
Keywords: natural synthetic; synthetic chalcones; nrf2 signaling; signaling pathway ... See more keywords
Anticancer Activity of Natural and Synthetic Chalcones
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DOI: 10.3390/ijms222111306
Abstract: Cancer is a condition caused by many mechanisms (genetic, immune, oxidation, and inflammatory). Anticancer therapy aims to destroy or stop the growth of cancer cells. Resistance to treatment is theleading cause of the inefficiency of… read more here.
Keywords: natural synthetic; synthetic chalcones; anticancer activity; anticancer ... See more keywords
Two Important Anticancer Mechanisms of Natural and Synthetic Chalcones
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DOI: 10.3390/ijms231911595
Abstract: ATP-binding cassette subfamily G and tubulin pharmacological mechanisms decrease the effectiveness of anticancer drugs by modulating drug absorption and by creating tubulin assembly through polymerization. A series of natural and synthetic chalcones have been reported… read more here.
Keywords: synthetic chalcones; anticancer mechanisms; mechanisms natural; natural synthetic ... See more keywords