Emissive Synthetic Cofactors: An Isomorphic, Isofunctional, and Responsive NAD+ Analogue.
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DOI: 10.1021/jacs.7b05852
Abstract: The synthesis, photophysics, and biochemical utility of a fluorescent NAD+ analogue based on an isothiazolo[4,3-d]pyrimidine core (NtzAD+) are described. Enzymatic reactions, photophysically monitored in real time, show NtzAD+ and NtzADH to be substrates for yeast… read more here.
Keywords: cofactors isomorphic; synthetic cofactors; emissive synthetic; analogue ... See more keywords