Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors
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DOI: 10.1016/j.isci.2021.102471
Abstract: Summary Synthetic strategies to activate cytokine receptors so far only address standard dimeric cytokine receptor assemblies. The 19 ligands of the tumor necrosis factor superfamily (TNFSF), however, form noncovalent trimers and receptor trimerization is considered… read more here.
Keywords: cytokine; cytokine receptors; fate decisions; synthetic cytokine ... See more keywords