Effects of cytokines derived from cancer-associated fibroblasts on androgen synthetic enzymes in estrogen receptor-negative breast carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-017-4464-5
Abstract: PurposeThe tumor microenvironment plays pivotal roles in promotion of many malignancies. Cancer-associated fibroblasts (CAFs) have been well-known to promote proliferation, angiogenesis, and metastasis but mechanistic understanding of tumor–stroma interactions is not yet complete. Recently, estrogen… read more here.
Keywords: breast carcinoma; synthetic enzymes; androgen synthetic; associated fibroblasts ... See more keywords
TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2020.08.011
Abstract: BACKGROUND While most skin diseases benefit from topical steroids, rosacea symptoms are exacerbated by topical steroids. In the rosacea pathogenesis, abnormal innate immune mechanisms including overexpression of the Toll-like receptor (TLR) have been proposed. However,… read more here.
Keywords: synthetic enzymes; tlr3; epidermal keratinocytes; glucocorticoid synthetic ... See more keywords