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Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity

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Published in 2021 at "Journal of Medicinal Chemistry"

DOI: 10.1021/acs.jmedchem.1c00896

Abstract: Modern adjuvants for vaccine formulations are immunostimulating agents whose action is based on the activation of pattern recognition receptors (PRRs) by well-defined ligands to boost innate and adaptive immune responses. Monophosphoryl lipid A (MPLA), a… read more here.

Keywords: synthetic glycolipids; activity; vaccine adjuvants; molecular vaccine ... See more keywords