Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα.
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DOI: 10.1182/bloodadvances.2018024950
Abstract: Fucoidans are sulfated fucose-based polysaccharides that activate platelets and have pro- and anticoagulant effects; thus, they may have therapeutic value. In the present study, we show that 2 synthetic sulfated α-l-fucoside-pendant glycopolymers (with average monomeric… read more here.
Keywords: aggregation; synthetic glycopolymers; glycopolymers natural; pear1 ... See more keywords