A 6-O-endosulfatase activity assay based on synthetic Heparan Sulfate oligomers.
Sign Up to like & getrecommendations! Published in 2023 at "Glycobiology"
DOI: 10.1093/glycob/cwad026
Abstract: Sulf-2 is an extracellular heparan 6-O-endosulfatase involved in the post-synthetic editing of heparan sulfate which regulates many important biological processes. Activity of the Sulf-2 and its substrate specificity remain insufficiently characterized in spite of more… read more here.
Keywords: heparan; heparan sulfate; synthetic heparan; endosulfatase activity ... See more keywords
The Effect of a Synthetic Heparan Sulfate on the Healing of Colonic Anastomoses
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DOI: 10.1155/2017/1078062
Abstract: Background The mimetic compound OTR4120 may replace endogenous-degraded heparan sulfates that normally maintain the bioactivity of growth factors that are important for tissue repair. Herein, we investigated the effect of OTR4120 on the healing of… read more here.
Keywords: synthetic heparan; effect synthetic; heparan sulfate; colonic anastomoses ... See more keywords
Synthetic Heparan Sulfate Mimetic Polymer Enhances Corneal Nerve Regeneration and Wound Healing after Experimental Laser Ablation Injury in Mice
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DOI: 10.3390/polym14224921
Abstract: (1) Background: Abnormal corneal wound healing compromises visual acuity and can lead to neuropathic pain. Conventional treatments usually fail to restore the injured corneal tissue. In this study, we evaluated the effectiveness of a synthetic… read more here.
Keywords: wound healing; laser; heparan sulfate; sulfate mimetic ... See more keywords