Synthetic hydrogels engineered to promote collecting lymphatic vessel sprouting.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121483
Abstract: The lymphatic vasculature is an essential component of the body's circulation providing a network of vessels to return fluid and proteins from the tissue space to the blood, to facilitate immune ce-ll and antigen transport… read more here.
Keywords: lymphatic vessel; engineered promote; hydrogels engineered; vessel ... See more keywords
Cytoskeletal stiffening in synthetic hydrogels
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-08569-4
Abstract: Although common in biology, controlled stiffening of hydrogels in vitro is difficult to achieve; the required stimuli are commonly large and/or the stiffening amplitudes small. Here, we describe the hierarchical mechanics of ultra-responsive hybrid hydrogels… read more here.
Keywords: cytoskeletal stiffening; stiffening synthetic; biology; synthetic hydrogels ... See more keywords
Non-invasive analysis of pancreas organoids in synthetic hydrogels defines material-cell interactions and luminal composition.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm00597a
Abstract: The cultivation of cells forming three-dimensional structures like organoids holds great potential in different fields of life sciences and is gaining increasing interest with regards to clinical applications and personalised medicine. However, conventional hydrogels used… read more here.
Keywords: cell interactions; material cell; microscopy; analysis pancreas ... See more keywords
Synthetic hydrogels identify matrix physicochemical properties required for renal epithelial cell tubulogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of cell science"
DOI: 10.1242/jcs.226639
Abstract: Synthetic hydrogels with controlled physicochemical matrix properties serve as powerful in vitro tools to dissect cell-extracellular matrix (ECM) interactions that regulate epithelial morphogenesis in 3D microenvironments. In addition, these fully defined matrices overcome the lot-to-lot… read more here.
Keywords: cell; matrix; properties required; epithelial tubulogenesis ... See more keywords
Reductionist Three-Dimensional Tumor Microenvironment Models in Synthetic Hydrogels
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14051225
Abstract: Simple Summary Tumors exist in a complex, three-dimensional environment which helps them to survive, grow, metastasize, and resist drug treatment. Simple, reproducible, in vitro models of this environment are necessary in order to better understand… read more here.
Keywords: tumor; three dimensional; tumor microenvironment; models synthetic ... See more keywords