2‐Isoxazolines: A Synthetic and Medicinal Overview
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DOI: 10.1002/cmdc.202000575
Abstract: Isoxazolines are nitrogen‐ and oxygen‐containing five‐membered heterocyclic scaffolds with extensive biological activities. This framework can be readily obtained in good to excellent yields through 1,3‐dipolar cycloaddition between nitrones with alkynes or allenes, aryl/alkyl halides, alkynes,… read more here.
Keywords: medicinal overview; synthetic medicinal; isoxazolines synthetic;
Recent advances in the synthetic and medicinal perspective of quinolones: A review.
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DOI: 10.1016/j.bioorg.2019.103291
Abstract: In the modern scenario, the quinolone scaffold has emerged as a very potent motif considering its clinical significance. Quinolones possess wide range of pharmacological activities such as anticancer, antibacterial, antifungal, antiprotozoal, antiviral, anti-inflammatory, carbonic anhydrase… read more here.
Keywords: synthetic medicinal; biological activities; quinolone based; chemistry ... See more keywords
Synthetic and Medicinal Perspective of Fused-Thiazoles as Anticancer Agents.
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DOI: 10.2174/1871520620666200728133017
Abstract: Fused triazole had explored their apartment as one of the important class of heterocycles, extensively used by chemists due to their diverse pharmacological activities in both synthetic organic chemistry and systemic biological field. Various methodologies… read more here.
Keywords: fused thiazoles; synthetic medicinal; anticancer agents; perspective fused ... See more keywords
An Appraisal on Synthetic and Medicinal Aspects of Fused Pyrimidines as Anti Neoplastic Agents.
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DOI: 10.2174/1871520622666220701113204
Abstract: Heterocyclic compounds are recognized to possess a high grade of structural diversity and a broad spectrum of therapeutic properties. About two-thirds of the New Chemical Entities approved by the FDA against cancer entails heterocyclic rings… read more here.
Keywords: medicinal aspects; appraisal synthetic; chemistry; fused pyrimidines ... See more keywords