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Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.04.066
Abstract: α-Santonin, a sesquiterpene lactone isolated from Artemisia Santonica, possesses diverse bioactivities including antioxidant, anti-inflammation, immunosuppressive, anti-roundworm, anti-malaria, etc. However, its bioactivities are not satisfactory and need to be further optimized. Thus, many α-santonin derivatives were…
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Keywords:
diverse bioactivities;
synthetic methodologies;
structure activity;
santonin derivatives ... See more keywords
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Published in 2023 at "RSC Advances"
DOI: 10.1039/d3ra02217j
Abstract: Natural goods, medications, and pharmaceutically active substances all contain substituted oxindoles. Generally, the C-3 stereocenter of the substituents of oxindoles and their absolute arrangement have a substantial impact on the bioactivity of these substances. In…
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Keywords:
related derivatives;
natural products;
synthetic methodologies;
oxindole related ... See more keywords
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Published in 2019 at "Synthetic Communications"
DOI: 10.1080/00397911.2019.1604967
Abstract: Abstract The development of new synthetic routes towards pyrazolo[1,5-a]pyrimidines for their biological and medicinal exploration is an attractive area for researchers. This review focuses on various synthetic routes developed in the last decade for the…
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Keywords:
methodologies pyrazolo;
recent synthetic;
pyrazolo pyrimidine;
synthetic methodologies ... See more keywords
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Published in 2020 at "Synthetic Communications"
DOI: 10.1080/00397911.2020.1786123
Abstract: Abstract Among heterocyclic compounds, pyridopyrazines are the scaffolds that have gained considerable attention on academic and industrial level due to their widespread applications as intermediates in the preparation of advanced and biologically potent pharmaceutical materials.…
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Keywords:
pyridopyrazines update;
methodologies pyridopyrazines;
recent synthetic;
synthetic methodologies ... See more keywords
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Published in 2022 at "Expert Opinion on Therapeutic Patents"
DOI: 10.1080/13543776.2022.2032649
Abstract: ABSTRACT Introduction Fluorine-18 is a promising radionuclide for developing novel PET radiotracers due to its characteristic features such as convenient half-life, metabolic stability, good imaging properties, and easy access to various clinical PET centers. Currently,…
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Keywords:
review;
methodologies pet;
synthetic methodologies;
imaging applications ... See more keywords
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Published in 2022 at "Expert opinion on therapeutic patents"
DOI: 10.1080/13543776.2022.2070003
Abstract: INTRODUCTION Carbon-11 is a short-lived radionuclide with versatile applications in synthetic methodologies to develop a variety of novel PET radiotracers. Different primary and secondary carbon-11 precursors are generated from cyclotron produced [11C]CO2 and used to…
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Keywords:
2012 2022;
synthetic methodologies;
carbon patents;
pet imaging ... See more keywords
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Published in 2018 at "Molecules"
DOI: 10.3390/molecules23112851
Abstract: Gold nanostructures that can be synthetically articulated to adapt diverse morphologies, offer a versatile platform and tunable properties for applications in a variety of areas, including biomedicine and diagnostics. Among several conformational architectures, gold nanoshells…
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Keywords:
nanoshells overview;
gold nanoshells;
methodologies gold;
synthetic methodologies ... See more keywords
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Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020240
Abstract: Indole-3-carbinol (I3C) is a natural product contained in vegetables belonging to the Brassicaceae family and has been studied in recent decades for its biological and pharmacological properties. Herein, we will analyze: (1) the biosynthetic processes…
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Keywords:
carbinol i3c;
synthetic methodologies;
i3c derivatives;
methodologies therapeutic ... See more keywords