Synthetic microbe communities provide internal reference standards for metagenome sequencing and analysis
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DOI: 10.1038/s41467-018-05555-0
Abstract: The complexity of microbial communities, combined with technical biases in next-generation sequencing, pose a challenge to metagenomic analysis. Here, we develop a set of internal DNA standards, termed “sequins” (sequencing spike-ins), that together constitute a… read more here.
Keywords: analysis; synthetic microbe; reference standards; microbe communities ... See more keywords