Combined evolutionary engineering and genetic manipulation improve low pH tolerance and butanol production in a synthetic microbial Clostridium community
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27333
Abstract: Synthetic microbial communities have become a focus of biotechnological research since they can overcome several of the limitations of single‐specie cultures. A paradigmatic example is Clostridium cellulovorans DSM 743B, which can decompose lignocellulose but cannot… read more here.
Keywords: evolutionary engineering; butanol; synthetic microbial; clostridium ... See more keywords
Design of synthetic microbial consortia for gut microbiota modulation.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2019.07.005
Abstract: The use of and interest in probiotics to modulate the human intestinal microbiota have strongly increased in recent years. However, most of the current probiotic products have been limited to single-strain formulations of easily culturable… read more here.
Keywords: microbiota; synthetic microbial; consortia gut; design synthetic ... See more keywords
Designing Synthetic Microbial Consortia for Biofuel Production.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2020.02.002
Abstract: Synthetic microbial consortia could efficiently produce biofuels from lignocellulose through labor division between different species. However, the incompatible growth conditions between lignocellulose degraders and biofuel producers might limit the overall conversion efficiency. We discuss recent… read more here.
Keywords: synthetic microbial; designing synthetic; consortia; biofuel production ... See more keywords
A Synthetic Microbial Community of Plant Core Microbiome Can Be a Potential Biocontrol Tool.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c08017
Abstract: Microbes are accepted as the foremost drivers of the rhizosphere ecology that influences plant health in direct or indirect ways. In recent years, the rapid development of gene sequencing technology has greatly facilitated the study… read more here.
Keywords: microbial community; core microbiome; synthetic microbial; plant core ... See more keywords
Indirect Enrichment of Desirable, but Less Fit Phenotypes, from a Synthetic Microbial Community Using Microdroplet Confinement.
Sign Up to like & getrecommendations! Published in 2023 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.3c00008
Abstract: Spatial structure within microbial communities can provide nearly limitless opportunities for social interactions and are an important driver for evolution. As metabolites are often molecular signals, metabolite diffusion within microbial communities can affect the composition… read more here.
Keywords: microbial community; indirect enrichment; synthetic microbial; community ... See more keywords
A Synthetic Microbial Operational Amplifier.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.8b00138
Abstract: Synthetic biology has created oscillators, latches, logic gates, logarithmically linear circuits, and load drivers that have electronic analogs in living cells. The ubiquitous operational amplifier, which allows circuits to operate robustly and precisely has not… read more here.
Keywords: operational amplifier; synthetic microbial; synthetic biology; biology ... See more keywords
Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
Sign Up to like & getrecommendations! Published in 2023 at "FEMS Microbiology Reviews"
DOI: 10.1093/femsre/fuad012
Abstract: Abstract The human gut harbors native microbial communities, forming a highly complex ecosystem. Synthetic microbial communities (SynComs) of the human gut are an assembly of microorganisms isolated from human mucosa or fecal samples. In recent… read more here.
Keywords: communities syncoms; synthetic microbial; syncoms human; microbial communities ... See more keywords
Combating biotic stresses in plants by synthetic microbial communities: Principles, applications and challenges
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Microbiology"
DOI: 10.1111/jam.15799
Abstract: Presently, agriculture worldwide is facing the major challenge of feeding the increasing population sustainably. The conventional practices have not only failed to meet the projected needs, but also led to tremendous environmental consequences. Hence, to… read more here.
Keywords: plants synthetic; combating biotic; synthetic microbial; biotic stresses ... See more keywords
Exchange of Vitamin B1 and Its Biosynthesis Intermediates Shapes the Composition of Synthetic Microbial Cocultures and Reveals Complexities of Nutrient Sharing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00503-21
Abstract: Vitamin B1 (thiamin) is an essential nutrient for cellular metabolism. Microorganisms that are unable to synthesize thiamin either fully or in part exogenously obtain it from their environment or via exchanges with other microbial members… read more here.
Keywords: exchange; synthetic microbial; microbial cocultures; thiamin ... See more keywords
Construction of Environmental Synthetic Microbial Consortia: Based on Engineering and Ecological Principles
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.829717
Abstract: In synthetic biology, engineering principles are applied to system design. The development of synthetic microbial consortia represents the intersection of synthetic biology and microbiology. Synthetic community systems are constructed by co-cultivating two or more microorganisms… read more here.
Keywords: microbial consortia; synthetic microbial; microbiology; construction ... See more keywords
Synthetic microbial consortia derived from rhizosphere soil protect wheat against a soilborne fungal pathogen
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.908981
Abstract: Synthetic microbial communities (SynComs) could potentially enhance some functions of the plant microbiome and emerge as a promising inoculant for improving crop performance. Here, we characterized a collection of bacteria, previously isolated from the wheat… read more here.
Keywords: wheat; microbial consortia; synthetic microbial; derived rhizosphere ... See more keywords