Structural Properties, Pathophysiological Relevance and Synthetic Modulators of TRPC Channels
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DOI: 10.1002/med.70007
Abstract: Transient receptor potential canonical (TRPC) channels, a subfamily of calcium‐permeable cation channels, regulate diverse physiological processes and are implicated in disorders including neurological conditions, cardiovascular diseases, and chronic kidney disease. Recent advances in cryo‐electron microscopy… read more here.
Keywords: trpc channels; properties pathophysiological; synthetic modulators; structural properties ... See more keywords
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-040320-103615
Abstract: The Wnt pathway is central to a host of developmental and disease-related processes. The remarkable conservation of this intercellular signaling cascade throughout metazoan lineages indicates that it coevolved with multicellularity to regulate the generation and… read more here.
Keywords: synthetic modulators; cell; pathway signaling; signaling mechanisms ... See more keywords