Synthetic Molecular Evolution of Cell Penetrating Peptides.
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DOI: 10.1007/978-1-0716-1752-6_5
Abstract: Rational design and optimization of cell penetrating peptides (CPPs) is difficult to accomplish because of the lack of quantitative sequence-structure-function rules describing the activity and because of the complex, poorly understood mechanisms of CPPs. Synthetic… read more here.
Keywords: cell penetrating; synthetic molecular; molecular evolution; penetrating peptides ... See more keywords
Application of Synthetic Molecular Evolution to the Discovery of Antimicrobial Peptides.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-3588-4_13
Abstract: Despite long-standing promise and many known examples, antimicrobial peptides (AMPs) have failed, with few exceptions, to significantly impact human medicine. Impediments to the systemic activity of AMPs include proteolysis, host cell interactions, and serum protein… read more here.
Keywords: medicine; molecular evolution; application synthetic; antimicrobial peptides ... See more keywords
A molecular assembler that produces polymers
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DOI: 10.1038/s41467-020-17814-0
Abstract: Molecular nanotechnology is a rapidly developing field, and tremendous progress has been made in developing synthetic molecular machines. One long-sought after nanotechnology is systems able to achieve the assembly-line like production of molecules. Here we… read more here.
Keywords: produces polymers; assembler; nanotechnology; molecular assembler ... See more keywords