Synthetic mycobacterial molecular patterns partially complete Freund’s adjuvant
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DOI: 10.1038/s41598-020-62543-5
Abstract: Complete Freund’s adjuvant (CFA) has historically been one of the most useful tools of immunologists. Essentially comprised of dead mycobacteria and mineral oil, we asked ourselves what is special about the mycobacterial part of this… read more here.
Keywords: molecular patterns; complete freund; freund adjuvant; synthetic mycobacterial ... See more keywords
Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle
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DOI: 10.1038/s41598-021-81474-3
Abstract: The cell wall of Mycobacterium tuberculosis is composed of diverse glycolipids which potentially interact with the human immune system. To overcome difficulties in obtaining pure compounds from bacterial extracts, we recently synthesized three forms of… read more here.
Keywords: synthetic mycobacterial; recognition; dat1 dat2; mincle ... See more keywords