Site-specific peak intensity ratio (SPIR) from 1D 2H/1H NMR spectra for rapid distinction between natural and synthetic nicotine and detection of possible adulteration
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02023-6
Abstract: Abstract1H and 2H NMR spectra of 4 natural and synthetic nicotine samples were collected in a non-quantitative way and site-specific 2H/1H peak intensity ratio (SPIR) was calculated for 12 distinct sites of nicotine. Experimental results… read more here.
Keywords: nicotine; synthetic nicotine; site specific; ratio ... See more keywords
Peptide-free Synthetic Nicotine Vaccine Candidates with α-Galactosylceramide as Adjuvant.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b01095
Abstract: Peptides are generally needed as T-helper epitopes in nicotine vaccines to induce effective antibody responses, but the highly polymorphic property of major histocompatibility complex (MHC) molecules may limit opportunities of B cell to receive CD4+… read more here.
Keywords: nicotine; synthetic nicotine; inkt; nicotine vaccine ... See more keywords
Synthetic nicotine descriptors: awareness and impact on perceptions of e-cigarettes among US youth
Sign Up to like & getrecommendations! Published in 2023 at "Tobacco Control"
DOI: 10.1136/tc-2023-057928
Abstract: Background Electronic cigarettes (e-cigarettes) are being advertised and sold with synthetic nicotine. Little research has examined youth awareness of synthetic nicotine or the impact of synthetic nicotine descriptors on perceptions of e-cigarettes. Methods Participants were… read more here.
Keywords: perceptions cigarettes; among youth; nicotine; impact ... See more keywords
Analysis and differentiation of tobacco-derived and synthetic nicotine products: Addressing an urgent regulatory issue
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DOI: 10.1371/journal.pone.0267049
Abstract: There is significant regulatory and economic need to distinguish analytically between tobacco-derived nicotine (TDN) and synthetic nicotine (SyN) in commercial products. Currently, commercial e-liquid and oral pouch products are available that contain tobacco-free nicotine, which… read more here.
Keywords: synthetic nicotine; tobacco; nicotine; analysis differentiation ... See more keywords