The Opioid Crisis-Not Just Opioids Anymore.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.15432
Abstract: Now in its second decade, the opioid epidemic has claimed more than 800 000 lives in the US, more than the combined total of all deaths in all US wars and armed conflicts from the… read more here.
Keywords: drug supply; synthetic opioids; drug; use ... See more keywords
Investigation of the μ and κ-opioid receptor activation by eight new synthetic opioids using the [35 S]-GTPγS assay: U-47700, isopropyl U-47700, U-49900, U-47931E, N-methyl U-47931E, U-51754, U-48520 and U-48800.
Sign Up to like & getrecommendations! Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3238
Abstract: In 2009 new synthetic opioids appeared on the new psychoactive substances market. This class of new psychoactive substances generally poses a health risk due to the high affinity and potency of most of these compounds… read more here.
Keywords: opioid receptor; synthetic opioids; using gtp; group ... See more keywords
Monoclonal Antibodies for Combating Synthetic Opioid Intoxication.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b04872
Abstract: Opioid abuse in the United States has been declared a national crisis and is exacerbated by an inexpensive, readily available and illicit supply of synthetic opioids. Specifically, fentanyl and related analogues such as carfentanil pose… read more here.
Keywords: monoclonal antibodies; opioid intoxication; synthetic opioids; antibodies combating ... See more keywords
Qualitative analysis of synthetic opioids, synthetic hallucinogens and LSD in urine using LC-MS/MS
Sign Up to like & getrecommendations! Published in 2019 at "Australian Journal of Forensic Sciences"
DOI: 10.1080/00450618.2019.1568565
Abstract: ABSTRACT Synthetic opioids and synthetic hallucinogens continue to expand in the illicit drugs market where they are designed and synthesized to avoid detection in routine drug tests. It is therefore crucial for laboratories to develop… read more here.
Keywords: synthetic opioids; analysis; oxo lsd; synthetic hallucinogens ... See more keywords
Gas Chromatography-Mass Spectrometry Analysis of Synthetic Opioids Belonging to the Fentanyl Class: A Review.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in analytical chemistry"
DOI: 10.1080/10408347.2021.1927668
Abstract: The rising number of deaths caused by fentanyl overdosing in the US due to the overwhelming illicit use of this synthetic opioid has started a global campaign to develop efficient ways to control its production… read more here.
Keywords: gas chromatography; mass spectrometry; analysis; synthetic opioids ... See more keywords
Prehospital Naloxone Administration Patterns During the Era of Synthetic Opioids.
Sign Up to like & getrecommendations! Published in 2023 at "Prehospital emergency care"
DOI: 10.1080/10903127.2023.2184886
Abstract: BACKGROUND The opioid epidemic is an ongoing public health emergency, exacerbated in recent years by the introduction and rising prevalence of synthetic opioids. The National EMS Scope of Practice Model was changed in 2017 to… read more here.
Keywords: synthetic opioids; naloxone administration; gcs scores; administration ... See more keywords
New Synthetic Opioids Use among Patients in Treatment for an Opioid Use Disorder in Barcelona
Sign Up to like & getrecommendations! Published in 2022 at "European Addiction Research"
DOI: 10.1159/000524011
Abstract: Introduction: New synthetic opioids (NSO), a class of new psychoactive substances (NPS), have recently emerged and pose an upcoming global public health challenge. The effects produced by NSO are similar to those from morphine, but… read more here.
Keywords: synthetic opioids; new synthetic; opioid use; treatment ... See more keywords
Has the United States Reached a Plateau in Overdoses Caused by Synthetic Opioids After the Onset of the COVID-19 Pandemic? Examination of Centers for Disease Control and Prevention Data to November 2021
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.947603
Abstract: Background Overdoses caused by synthetic mu-opioid receptor (MOR) agonists such as fentanyl are causing increasing mortality in the United States. The COVID-19 pandemic continues to have complex effects on public health, including opioid use disorders… read more here.
Keywords: period; synthetic opioids; mortality; covid pandemic ... See more keywords