Articles with "synthetic pathway" as a keyword



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A Versatile Synthetic Pathway for Producing Mesostructured Plasmonic Nanostructures.

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Published in 2022 at "Small"

DOI: 10.1002/smll.202203940

Abstract: Highly branched gold (Au) nanostructures with sharp tips are considered excellent substrates for surface-enhanced Raman scattering (SERS)-based sensing technologies. Here, a simple synthetic route for producing Au or Au-Ag bimetallic mesostructures with multiple sharpened tips… read more here.

Keywords: synthetic pathway; producing mesostructured; pathway producing; mesostructured plasmonic ... See more keywords
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Reduction of mitochondrial 3-oxoacyl-ACP synthase (OXSM) by hyperglycemia is associated with deficiency of α-lipoic acid synthetic pathway in kidney of diabetic mice.

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Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.02.155

Abstract: LA (alpha-Lipoic acid) deficiency represents a risk factor in the pathogenesis of diabetic complications as synthetic LA is routinely used in the treatment of the complications in patients. The mechanism underlying LA deficiency remains elusive… read more here.

Keywords: reduction; synthetic pathway; diabetic mice; deficiency ... See more keywords
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Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction.

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Published in 2019 at "Placenta"

DOI: 10.1016/j.placenta.2019.05.012

Abstract: OBJECTIVES Placental insufficiency contributes to altered maternal-fetal amino acid transfer, and thereby to poor fetal growth. An important placental function is the uptake of tryptophan and its metabolism to serotonin (5-HT) and kynurenine metabolites, which… read more here.

Keywords: control; fetal growth; growth restriction; placental serotonin ... See more keywords

Challenges and Opportunities in the Development of Serine Synthetic Pathway Inhibitors for Cancer Therapy.

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Published in 2017 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.6b01167

Abstract: Recent advances in the understanding of the relationship between cancer and metabolism have highlighted the relevance of the serine synthetic pathway (SSP), which consists of three successive enzymatic reactions. Enzymes of the SSP, such as… read more here.

Keywords: cancer; chemistry; synthetic pathway; serine synthetic ... See more keywords
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Three-Step Synthetic Pathway toward Fully Decorated [1,2,3]Triazolo[4,5-d]pyrimidine (8-Azapurine) Derivatives.

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Published in 2023 at "Organic letters"

DOI: 10.1021/acs.orglett.3c00729

Abstract: [1,2,3]Triazolo[4,5-d]pyrimidines (8-azapurines) are known bioisosteres of the purine nucleus. A step-efficient synthesis of 8-azapurines, in particular 6-alkyl derivatives, is currently unavailable. This work focuses on a three-step synthetic pathway for the synthesis of fully decorated… read more here.

Keywords: synthetic pathway; step; fully decorated; step synthetic ... See more keywords

Construction of a synthetic pathway for the production of 1,3-propanediol from glucose

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-48091-7

Abstract: In this work, we describe the construction of a synthetic metabolic pathway enabling direct biosynthesis of 1,3-propanediol (PDO) from glucose via the Krebs cycle intermediate malate. This non-natural pathway extends a previously published synthetic pathway… read more here.

Keywords: construction synthetic; pdo; synthetic pathway; pathway ... See more keywords
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Engineering a Synthetic Pathway for Gentisate in Pseudomonas Chlororaphis P3

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Published in 2020 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2020.622226

Abstract: Pseudomonas chlororaphis P3 has been well-engineered as a platform organism for biologicals production due to enhanced shikimate pathway and excellent physiological and genetic characteristics. Gentisate displays high antiradical and antioxidant activities and is an important… read more here.

Keywords: pseudomonas chlororaphis; synthetic pathway; engineering synthetic; pathway gentisate ... See more keywords
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Triterpenoids in Jujube: A Review of Composition, Content Diversity, Pharmacological Effects, Synthetic Pathway, and Variation during Domestication

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Published in 2023 at "Plants"

DOI: 10.3390/plants12071501

Abstract: Chinese jujube (Ziziphus jujuba Mill.) and its wild ancestor, sour jujube (Z. acidojujuba C.Y. Cheng & M.J. Liu), is a Ziziphus genus in the Rhamnaceae family. ZJ and ZA are rich in a variety of… read more here.

Keywords: synthetic pathway; jujube; domestication triterpenoids; triterpenoids jujube ... See more keywords