Single nucleotide genome recognition and selective bacterial lysis using synthetic phages loaded with CRISPR-Cas12f1-truncated sgRNA.
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DOI: 10.71150/jm.2501012
Abstract: Phage specificity primarily relies on host cell-surface receptors. However, integrating cas genes and guide RNAs into phage genomes could enhance their target specificity and regulatory effects. In this study, we developed a CRISPR-Cas12f1 system-equipped bacteriophage… read more here.
Keywords: cas12f1 truncated; crispr cas12f1; single nucleotide; synthetic phages ... See more keywords