Evaluation of synthetic promoters in Physcomitrella patens.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.092
Abstract: Securing a molecular toolbox including diverse promoters is essential for genome engineering. However, native promoters have limitations such as the available number or the length of the promoter. In this work, three short synthetic promoters… read more here.
Keywords: promoters physcomitrella; physcomitrella patens; synthetic promoters; expression ... See more keywords
Bioinformatic Design of Dendritic Cell-Specific Synthetic Promoters
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00027
Abstract: Next-generation DNA vectors for cancer immunotherapies and vaccine development require promoters eliciting predefined transcriptional activities specific to target cell types, such as dendritic cells (DCs), which underpin immune response. In this study, we describe the… read more here.
Keywords: promoter; cell; specific synthetic; design ... See more keywords
Challenges and advances towards the rational design of microalgal synthetic promoters in Chlamydomonas reinhardtii.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad100
Abstract: Microalgae hold the enormous potential to provide a safe and sustainable source of high-value compounds, acting as carbon-fixing biofactories that could help to mitigate rapidly progressing climate change. Bioengineering microalgal strains will be key to… read more here.
Keywords: challenges advances; rational design; chlamydomonas reinhardtii; synthetic promoters ... See more keywords
Rational design of minimal synthetic promoters for plants
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa682
Abstract: Abstract Promoters serve a critical role in establishing baseline transcriptional capacity through the recruitment of proteins, including transcription factors. Previously, a paucity of data for cis-regulatory elements in plants meant that it was challenging to… read more here.
Keywords: plant; synthetic promoters; rational design; minimal synthetic ... See more keywords
Context‐dependency of synthetic minimal promoters in driving gene expression: a case study
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13489
Abstract: Synthetic promoters are considered ideal candidates in driving robust gene expression. Most of the available synthetic promoters are minimal promoters, for which the upstream sequence of the 5′ end of the core region is usually… read more here.
Keywords: upstream sequence; synthetic promoters; minimal promoters; gene expression ... See more keywords
Functional analysis of soybean cyst nematode-inducible synthetic promoters and their regulation by biotic and abiotic stimuli in transgenic soybean (Glycine max)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.988048
Abstract: We previously identified cis-regulatory motifs in the soybean (Glycine max) genome during interaction between soybean and soybean cyst nematode (SCN), Heterodera glycines. The regulatory motifs were used to develop synthetic promoters, and their inducibility in… read more here.
Keywords: soybean cyst; glycine max; synthetic promoters; soybean glycine ... See more keywords
The Expression of CARK1 or RCAR11 Driven by Synthetic Promoters Increases Drought Tolerance in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19071945
Abstract: Drought stress hinders plant growth and development, and abscisic acid (ABA) stimulates plants to respond to drought. Here, to increase plant tolerance to drought, we designed three synthetic promoters (Ap, Dp, ANDp) to determine transcription… read more here.
Keywords: rcar11; tolerance; cark1 rcar11; synthetic promoters ... See more keywords