Articles with "synthetic rescue" as a keyword



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High-throughput synthetic rescue for exhaustive characterization of suppressor mutations in human genes

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Published in 2020 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-020-03519-6

Abstract: Inherited or acquired mutations can lead to pathological outcomes. However, in a process defined as synthetic rescue, phenotypic outcome created by primary mutation is alleviated by suppressor mutations. An exhaustive characterization of these mutations in… read more here.

Keywords: exhaustive characterization; synthetic rescue; suppressor; suppressor mutations ... See more keywords