Synthetic Retinoid Kills Drug‐Resistant Cancer Stem Cells via Inducing RARγ‐Translocation‐Mediated Tension Reduction and Chromatin Decondensation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203173
Abstract: A recently developed synthetic retinoid abrogates proliferation and induces apoptosis of drug‐resistant malignant‐cancer‐stem‐cell‐like cells. However, the underlying mechanisms of how the synthetic retinoid induces cancer‐stem‐cell‐like cell tumor‐repopulating cell (TRC) apoptosis are elusive. Here, it is… read more here.
Keywords: cancer stem; synthetic retinoid; tension; retinoid ... See more keywords
Stabbed while Sleeping: Synthetic Retinoid Antibiotics Kill Bacterial Persister Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.05.029
Abstract: Antibiotic-tolerant persister cells are difficult to eradicate by conventional classes of antibiotics. Kim and colleagues have discovered a new class of synthetic retinoid antibiotics that kill Staphylococcus aureus persisters by disrupting their cytoplasmic membrane. read more here.
Keywords: synthetic retinoid; retinoid antibiotics; persister cells; antibiotics kill ... See more keywords
Jojoba Oil Soft Colloidal Nanocarrier of a Synthetic Retinoid: Preparation, Characterization and Clinical Efficacy in Psoriatic Patients.
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DOI: 10.2174/1567201813666160513132321
Abstract: BACKGROUND Nanotechnology has provided substantial benefits in drug delivery, especially in the treatment of dermatological diseases. Psoriasis is a chronic inflammatory skin disease in which topical delivery of antipsoriatic agents is considered the first line… read more here.
Keywords: microemulsion; jojoba oil; psoriatic patients; synthetic retinoid ... See more keywords
Development and Challenges of Synthetic Retinoid Formulations in Cancer.
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DOI: 10.2174/1567201819666220810094708
Abstract: Retinoids represent a class of chemical compounds derived from, or structurally and functionally related to vitamin A. Retinoids play crucial roles in regulating a range of crucial biological processes spanning embryonic development to adult life.… read more here.
Keywords: development; synthetic retinoid; development challenges; challenges synthetic ... See more keywords