Synthetic Riboswitches: From Plug and Pray toward Plug and Play.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.6b01218
Abstract: In synthetic biology, metabolic engineering, and gene therapy, there is a strong demand for orthogonal or externally controlled regulation of gene expression. Here, RNA-based regulatory devices represent a promising emerging alternative to proteins, allowing a… read more here.
Keywords: pray toward; toward plug; plug pray; riboswitches plug ... See more keywords
A Theophylline-Responsive Riboswitch Regulates Expression of Nuclear-Encoded Genes1[OPEN].
Sign Up to like & getrecommendations! Published in 2020 at "Plant physiology"
DOI: 10.1104/pp.19.00625
Abstract: Riboswitches are small cis-regulatory RNA elements that regulate gene expression by conformational changes in response to ligand binding. Synthetic riboswitches have been engineered as versatile and innovative tools for gene regulation by external application of… read more here.
Keywords: theophylline responsive; gene expression; nuclear encoded; gene ... See more keywords
Synthetic riboswitches for the analysis of tRNA processing by eukaryotic RNase P enzymes
Sign Up to like & getrecommendations! Published in 2022 at "RNA"
DOI: 10.1261/rna.078814.121
Abstract: Removal of the 5′-leader region is an essential step in the maturation of tRNA molecules in all domains of life. This reaction is catalyzed by various RNase P activities, ranging from ribonucleoproteins with ribozyme activity… read more here.
Keywords: eukaryotic rnase; riboswitches analysis; rnase; rnase enzymes ... See more keywords