Synthetic study of solanoeclepin A: Cyclobutane cyclization via SmI2-additive-mediated reaction and D ring functionalization
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.03.065
Abstract: Abstract The construction of tricyclo[5.2.1.01,6]decene skeleton was achieved by cyclobutane ring formation via improved radical reaction using SmI2-H2O-HFIP and SmI2-LiCl conditions in good yields. Those additives were studied to increase the reactivity of SmI2. Two… read more here.
Keywords: solanoeclepin cyclobutane; cyclization via; synthetic study; cyclobutane cyclization ... See more keywords
Synthetic Study Aiming at the Tricyclic Core of 12-epi-JBIR-23/24.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c00853
Abstract: The synthetic study toward highly enantio- and diastereoselective synthesis of the tricyclic framework of 12-epi-JBIR-23/24, a natural product analogue showing inhibitory activity against four malignant pleural mesothelioma cell lines, is presented herein. In this synthesis,… read more here.
Keywords: study aiming; epi jbir; core; synthetic study ... See more keywords
Synthetic Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core Framework.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01257
Abstract: The cyclopentane core framework 23 of pactamycin (1) was synthesized in 14 steps from symmetric cyclohexadiene 11. Our synthetic strategy features Rh-mediated catalytic desymmetrization of 10 via aziridination and then regioselective ring-opening reaction of sulfonylaziridine… read more here.
Keywords: cyclopentane core; core framework; synthetic study;
Synthetic Study toward Total Synthesis of (±)-Germine: Synthesis of (±)-4-Methylenegermine.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b02434
Abstract: The total synthesis of 4-methylenegermine is described. read more here.
Keywords: synthesis methylenegermine; synthetic study; total synthesis; study toward ... See more keywords
Synthetic Study on Acremoxanthone A, Part 2: Model Study on the EFG Xanthone Moiety through a Nitrile Oxide Cycloaddition–SNAr Sequence
Sign Up to like & getrecommendations! Published in 2020 at "Synlett"
DOI: 10.1055/a-1303-5613
Abstract: Toward a total synthesis of acremoxanthone A, we report a model study on the construction of the EFG ring system. The key steps include (1) an intermolecular 1,3-dipolar cycloaddition of an aryl nitrile oxide with… read more here.
Keywords: cycloaddition; model study; nitrile oxide; study ... See more keywords
Synthetic Study toward Triterpenes from the Schisandraceae Family of Natural Products
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114468
Abstract: Triterpenoid natural products from the Schisandraceae family have long presented a significant synthetic challenge. Lancifodilactone I, a member of the family not previously synthesized, was identified as a key natural product target, from which many… read more here.
Keywords: study toward; family; natural products; ring system ... See more keywords
Synthetic study toward the diterpenoid aberrarone
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.18.173
Abstract: An approach to aberrarone, an antimalarial diterpenoid natural product with tetracyclic skeleton is reported. Key to the stereoselective preparation of the 6-5-5 tricyclic skeleton includes the mediation of Nagata reagent for constructing the C1 all-carbon… read more here.
Keywords: study toward; synthetic study; diterpenoid aberrarone; chemistry ... See more keywords
Synthetic study toward tridachiapyrone B
Sign Up to like & getrecommendations! Published in 2022 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.18.183
Abstract: A convergent approach to the skeleton of tridachiapyrone B is described taking advantage of the desymmetrization of α,α’-dimethoxy-γ-pyrone leading to α-crotyl-α’-methoxy-γ-pyrone in one step. To construct the quaternary carbon of the 2,5-cyclohexadienone of the target,… read more here.
Keywords: study toward; toward tridachiapyrone; pyrone; tridachiapyrone ... See more keywords