E6020, a synthetic TLR4 agonist, accelerates myelin debris clearance, Schwann cell infiltration, and remyelination in the rat spinal cord
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DOI: 10.1002/glia.23132
Abstract: Oligodendrocyte progenitor cells (OPCs) are present throughout the adult brain and spinal cord and can replace oligodendrocytes lost to injury, aging, or disease. Their differentiation, however, is inhibited by myelin debris, making clearance of this… read more here.
Keywords: synthetic tlr4; cord; myelin debris; tlr4 agonist ... See more keywords