Articles with "synthorx inc" as a keyword



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THOR-707, a novel not-alpha IL-2, promotes all key immune system anti-tumoral actions of IL-2 without eliciting vascular leak syndrome (VLS)

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Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz253.051

Abstract: Abstract Background THOR-707 is a reprogrammed, site-directed, single pegylated, recombinant human IL-2 (rIL-2) variant that lacks binding affinity for the α chain of the IL-2 receptor. Because THOR-707 has near-native binding affinity for the βγ… read more here.

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