Articles with "synuclein brain" as a keyword



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Neuronal hyperactivity–induced oxidant stress promotes in vivo α-synuclein brain spreading

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Published in 2022 at "Science Advances"

DOI: 10.1126/sciadv.abn0356

Abstract: Interneuronal transfer and brain spreading of pathogenic proteins are features of neurodegenerative diseases. Pathophysiological conditions and mechanisms affecting this spreading remain poorly understood. This study investigated the relationship between neuronal activity and interneuronal transfer of… read more here.

Keywords: brain spreading; hyperactivity induced; neuronal hyperactivity; hyperactivity ... See more keywords