α‐Synuclein Gene Hypomethylation in LRRK2 Parkinson's Disease Patients
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DOI: 10.1002/mds.30094
Abstract: α‐Synuclein (SNCA) gene hypomethylation was reported in idiopathic Parkinson's disease (iPD). Based on a high clinical resemblance between iPD and leucine‐rich repeat kinase 2 (LRRK2)‐driven Parkinson's disease (L2PD), we investigated the epigenetic status of SNCA… read more here.
Keywords: gene hypomethylation; disease; parkinson disease; synuclein gene ... See more keywords
Drift diffusion model of reward and punishment learning in rare alpha-synuclein gene carriers
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neurogenetics"
DOI: 10.1080/01677063.2017.1301939
Abstract: Abstract To understand the cognitive effects of alpha-synuclein polymorphism, we employed a drift diffusion model (DDM) to analyze reward- and punishment-guided probabilistic learning task data of participants with the rare alpha-synuclein gene duplication and age-… read more here.
Keywords: drift diffusion; alpha synuclein; synuclein gene;