α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies
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DOI: 10.1038/s41598-018-30808-9
Abstract: Aggregation of α-synuclein, the hallmark of α-synucleinopathies such as Parkinson’s disease, occurs in various glycosphingolipidoses. Although α-synuclein aggregation correlates with deficiencies in the lysosomal degradation of glycosphingolipids (GSL), the mechanism(s) involved in this aggregation remains… read more here.
Keywords: synuclein aggregation; aggregation; synuclein interacts; interacts directly ... See more keywords