α-synuclein in the pathophysiology of Alzheimer’s disease
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DOI: 10.1186/s13024-019-0320-x
Abstract: The Alzheimer’s disease (AD) afflicted brain is neuropathologically defined by extracellular amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein. However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn), mainly associated… read more here.
Keywords: pathophysiology alzheimer; alzheimer disease; disease; evidence ... See more keywords