Predictive Modeling of Neurotoxic α-Synuclein Polymorphs.
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DOI: 10.1007/978-1-0716-1546-1_17
Abstract: Assembly of monomeric α-synuclein (αS) into aggregation-resistant helically folded tetramers and related multimers is a key target for Parkinson's disease (PD). Protein dynamics hampers experimental characterization of the polymorphism of these structures and so computational… read more here.
Keywords: synuclein; modeling neurotoxic; synuclein polymorphs; neurotoxic synuclein ... See more keywords