Phenotypic Heterogeneity in α‐Synucleinopathies: Straining the Difference
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders"
DOI: 10.1002/mds.28013
Abstract: α-Synucleinopathies are a heterogeneous group of progressive neurodegenerative disorders characterized by the presence of α-synuclein aggregates and include Parkinson’s disease (PD), dementia with Lewy bodies, and multiple system atrophy (MSA). In disease, α-synuclein is believed… read more here.
Keywords: synuclein; disease; pathology; synuclein strains ... See more keywords
The Concept of α-Synuclein Strains and How Different Conformations May Explain Distinct Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.737195
Abstract: In the past few years, an increasing amount of studies primarily based on experimental models have investigated the existence of distinct α-synuclein strains and their different pathological effects. This novel concept could shed light on… read more here.
Keywords: synuclein; concept synuclein; neurodegenerative disorders; disease ... See more keywords