Syringin Prevents Aβ25-35-Induced Neurotoxicity in SK-N-SH and SK-N-BE Cells by Modulating miR-124-3p/BID Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical research"
DOI: 10.1007/s11064-021-03240-1
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder disease, disturbing people's normal life. Syringin was mentioned to antagonize Amyloid-β (Aβ)-induced neurotoxicity. However, the action mechanism is still not fully elucidated. This study aimed to explore a… read more here.
Keywords: induced neurotoxicity; syringin; bid; mir 124 ... See more keywords
Syringin protects against colitis by ameliorating inflammation.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108242
Abstract: Inflammatory bowel disease (IBD) is a chronic inflammatory condition with high incidence. Syringin exhibits multiple pharmacological properties, including anti-inflammatory effects. However, the effect of syringin on inflammation of IBD is still unclear. Here, the dextran… read more here.
Keywords: syringin; inflammation; colitis ameliorating; syringin protects ... See more keywords
Syringin attenuates insulin resistance via adiponectin-mediated suppression of low-grade chronic inflammation and ER stress in high-fat diet-fed mice.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.05.003
Abstract: In the treatment of type 2 diabetes, improvements in glucose control are often linked to side effects such as weight gain and altered lipid metabolism, increasing the risk of cardiovascular disease. It is therefore important… read more here.
Keywords: syringin; inflammation; stress; high fat ... See more keywords
Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2016.2824
Abstract: Syringin, extracted from Eleutherococcus senticosus, is a major biologically active component of Chinese herbs. Studies have certified the multiple pharmacological properties of syringin. However, the role of syringin in cardiac hypertrophy and the mechanisms involved… read more here.
Keywords: cardiac hypertrophy; hypertrophy induced; aortic banding; syringin ... See more keywords