Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2018.11.007
Abstract: Summary Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have emerged as a promising cardiac safety platform, demonstrated by numerous validation studies using drugs with known cardiac adverse effects in humans. However, the challenge remains to… read more here.
Keywords: hazard; cardiac hazard; system cardiac; safety ... See more keywords
External Validation of European System for Cardiac Operative Risk Evaluation II (EuroSCORE II) for Risk Prioritization in an Iranian Population
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Cardiovascular Surgery"
DOI: 10.21470/1678-9741-2017-0030
Abstract: Introduction The European System for Cardiac Operative Risk Evaluation II (EuroSCORE II) is a prediction model which maps 18 predictors to a 30-day post-operative risk of death concentrating on accurate stratification of candidate patients for… read more here.
Keywords: risk; risk evaluation; system cardiac; european system ... See more keywords