Molecular neurobiology of mTOR
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2016.11.017
Abstract: Mammalian/mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that controls several important aspects of mammalian cell function. mTOR activity is modulated by various intra- and extracellular factors; in turn, mTOR changes rates of translation,… read more here.
Keywords: nervous system; mtor; neurobiology; mtor activity ... See more keywords
Parthanatos in the pathogenesis of nervous system diseases
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DOI: 10.1016/j.neuroscience.2020.09.049
Abstract: Parthanatos is a modality of regulated cell death initiated by poly(ADP-ribose) polymerase 1(PARP-1) hyperactivation and characterized by apoptosis inducing factor (AIF)-dependent and microphage migration inhibitory factor (MIF)-dependent DNA degradation. It is a caspase-independent, mitochondrial-linked paradigm… read more here.
Keywords: nervous system; parthanatos pathogenesis; pathogenesis nervous; system diseases ... See more keywords
α-Lipoic acid, functional fatty acid, as a novel therapeutic alternative for central nervous system diseases: A review
Sign Up to like & getrecommendations! Published in 2019 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2017.1386755
Abstract: Objectives: α-lipoic acid (ALA) is a natural antioxidant which acts as a cofactor of bioenergetic mitochondrial enzymes. Along with its mitochondrial action, ALA and its reduced form have many biological functions resulting in a wide… read more here.
Keywords: system diseases; central nervous; lipoic acid; nervous system ... See more keywords
The role of curcumin in the liver-gut system diseases: from mechanisms to clinical therapeutic perspective.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2023.2204349
Abstract: Natural products have provided abundant sources of lead compounds for new drug discovery and development over the past centuries. Curcumin is a lipophilic polyphenol isolated from turmeric, a plant used in traditional Asian medicine for… read more here.
Keywords: curcumin; gut system; curcumin liver; system diseases ... See more keywords
The efficacy, effectiveness, and safety of Kyung-ok-ko: A narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031311
Abstract: Kyung-ok-ko (KOK), a traditional medicinal formula in East Asia, has been recently studied across various fields. However, comprehensive reviews of clinical applications of KOK targeting clinical and experimental studies are lacking. Therefore, the application of… read more here.
Keywords: system; safety; activity; efficacy effectiveness ... See more keywords
Chinese expert consensus on the application of live combined Bifidobacterium, Lactobacillus, and Enterococcus powder/capsule in digestive system diseases (2021).
Sign Up to like & getrecommendations! Published in 2023 at "Journal of gastroenterology and hepatology"
DOI: 10.1111/jgh.16195
Abstract: BACKGROUND AND AIM Disturbance of gut microbiota is associated with pathological change in multiple diseases. Probiotics can improve symptoms and exert clinical effects via regulation of gastrointestinal microecological environments, and a probiotic product commonly dispensed… read more here.
Keywords: system; consensus; digestive system; bifidobacterium lactobacillus ... See more keywords
Mitochondria Related Cell Death Modalities and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.832356
Abstract: Mitochondria are well known as the centre of energy metabolism in eukaryotic cells. However, they can not only generate ATP through the tricarboxylic acid cycle and oxidative phosphorylation but also control the mode of cell… read more here.
Keywords: cell death; system diseases; modes cell; death ... See more keywords
The role of TIGAR in nervous system diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1023161
Abstract: TP53-induced glycolysis and apoptosis regulator (TIGAR) mainly regulates pentose phosphate pathway by inhibiting glycolysis, so as to synthesize ribose required by DNA, promote DNA damage repair and cell proliferation, maintain cell homeostasis and avoid body… read more here.
Keywords: tigar; role tigar; system diseases; nervous system ... See more keywords
Glymphatic System Dysfunction in Central Nervous System Diseases and Mood Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.873697
Abstract: The glymphatic system, a recently discovered macroscopic waste removal system in the brain, has many unknown aspects, especially its driving forces and relationship with sleep, and thus further explorations of the relationship between the glymphatic… read more here.
Keywords: system; central nervous; diseases mood; system diseases ... See more keywords
Application of extracorporeal shock wave therapy in nervous system diseases: A review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.963849
Abstract: Neurological disorders are one of the leading causes of morbidity and mortality worldwide, and their therapeutic options remain limited. Recent animal and clinical studies have shown the potential of extracorporeal shock wave therapy (ESWT) as… read more here.
Keywords: neurological disorders; extracorporeal shock; wave therapy; system diseases ... See more keywords
A mini-review of the role of condensin in human nervous system diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.889796
Abstract: Mitosis and meiosis are crucial life activities that transmit eukaryotic genetic information to progeny in a stable and orderly manner. The formation and appearance of chromosomes, which are derived from chromatin, are the preconditions and… read more here.
Keywords: role; condensin; mini review; system diseases ... See more keywords