Articles with "system gpx4" as a keyword



Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway

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Published in 2025 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2024.1504114

Abstract: Introduction Cerebral ischemia–reperfusion (IR) causes severe secondary brain injury. Previous studies have demonstrated that ferroptosis is involved in IR-induced brain injury. However, whether IR induces ferroptosis in brain microvascular endothelial cells (BMVECs) is not fully… read more here.

Keywords: gpx4 pathway; analysis; system gpx4; ferroptosis ... See more keywords